ID   U7PNL0_SPOS1            Unreviewed;      1121 AA.
AC   U7PNL0;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN   ORFNames=HMPREF1624_07422 {ECO:0000313|EMBL:ERS96506.1};
OS   Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS   disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX   NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS96506.1, ECO:0000313|Proteomes:UP000018087};
RN   [1] {ECO:0000313|Proteomes:UP000018087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58251 / de Perez 2211183
RC   {ECO:0000313|Proteomes:UP000018087};
RX   PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA   Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA   Goldberg J., Young S., Zeng Q., Birren B.W.;
RT   "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT   58251).";
RL   Genome Announc. 2:E0044614-E0044614(2014).
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DR   EMBL; KI440850; ERS96506.1; -; Genomic_DNA.
DR   AlphaFoldDB; U7PNL0; -.
DR   eggNOG; ENOG502SIWU; Eukaryota.
DR   HOGENOM; CLU_008134_0_0_1; -.
DR   OrthoDB; 1823732at2759; -.
DR   Proteomes; UP000018087; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10039; AMELOGENIN; 1.
DR   PANTHER; PTHR10039:SF17; NACHT DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018087}.
FT   DOMAIN          364..512
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          67..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1121 AA;  125787 MW;  52E96E28550A2FDA CRC64;
     MSSSTRNNSG LRHRIREHLR IRSRSRNRSK NEDYESTSAL GAIAASSSDA SSQNATLTIV
     SLSLESTADP AQDRSTTGDT TSEKQLDRNT LHAVLYTSGA KQDPLVSGEP LGADTDVSGG
     DGADLWSAAY REAVNSLGED VNVAILKGDN VSQLFRQLEE MDKESSKDSA FVRDLAAPLA
     SIEPTAGTVV GVVRSVTAIA ISMSTADAQF AMQIGDMLEQ ISYIDDCDTL GQKTNKTDIY
     KALVSVYRKL LEFYSAAFEI LTKKGAKLVM KMVLEHGRLP KVVNDFLKQA DNLRRLVQKA
     TWEIVEDIRA MLYDQEISRW LDSGKISRQS QQHASLRDVC ADQACELLLK DTKFIRWYAA
     SGSEQLAIVG DMGQGKTVAM AFLIDELSRR NERQLPRPKI CYHYCRDDET GQAIHIFATL
     ILSLLAQLSG LKRVFFEWYK RTEVSGIYDP AKNTKKLEEF LHQTVQSLDR PLFIVIDGLD
     ECDRASRNTV LESLNALSQK TPSLKVLLST RPEEEILVRL NETARIYLVS NAERDRIIVR
     KLVERQLHFL AKDVKDLVFE KLSLLARGSA IWTRMVIELI EVRRIRAIAP MRAFLENIPP
     PGQLSELYVN IFSRYTANDP DNQKLATTAL EVLAVSRRPL SVLELAWAVA MGVSQEGLTT
     VAALSQQVDH QRILGLIQPF ISHVDFSDVN KRQVTLAHKS VYEFIIYGWI TSQPGLEGLP
     IPTTANELLI QQRIASLGAA LMDICVRYLL LDDIGSKNLF TDEQLIIDEL PQEFDLFGDS
     NEPTDYDPCC TWESFEENMI RFDPIGRGFG EFFTYASCHW LDHYGTATLA PTPGKIETLC
     QAGSMRLHNW ITQNCRPGCT LKPRFPFDSS RYDPLGINAL FGSKVMLRHM IQTADFDDGN
     FFPDTAMRAA EQIILSGDRS RLRILFTGGQ VCQQLQTLDF FRLVMKLWAA SDRLAQDWDT
     IFDFVSRVLD SMVQDRWGNE LLCSAAGWGC MPILERLMTG AQQNEALRTE LLRDCHREYK
     FGVVGKAAHQ SIGEAVSGNH VDVVAYLLGQ KGIEAHLRYR NSRGENVFHL ASGNCNPAMF
     RLLVRHFKEG VHQTDHQQCS LVQNTGCPEM RSSGVFKWQP N
//