ID   U7PP02_SPOS1            Unreviewed;       434 AA.
AC   U7PP02;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=FAD-binding domain-containing protein {ECO:0000259|Pfam:PF01494};
GN   ORFNames=HMPREF1624_07139 {ECO:0000313|EMBL:ERS96230.1};
OS   Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS   disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX   NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS96230.1, ECO:0000313|Proteomes:UP000018087};
RN   [1] {ECO:0000313|Proteomes:UP000018087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58251 / de Perez 2211183
RC   {ECO:0000313|Proteomes:UP000018087};
RX   PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA   Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA   Goldberg J., Young S., Zeng Q., Birren B.W.;
RT   "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT   58251).";
RL   Genome Announc. 2:E0044614-E0044614(2014).
CC   -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC       {ECO:0000256|ARBA:ARBA00007992}.
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DR   EMBL; KI440850; ERS96230.1; -; Genomic_DNA.
DR   AlphaFoldDB; U7PP02; -.
DR   STRING; 1391915.U7PP02; -.
DR   eggNOG; KOG2614; Eukaryota.
DR   HOGENOM; CLU_009665_19_5_1; -.
DR   OrthoDB; 5491711at2759; -.
DR   Proteomes; UP000018087; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR13789:SF316; FAD-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13789; MONOOXYGENASE; 1.
DR   Pfam; PF01494; FAD_binding_3; 2.
DR   PRINTS; PR00420; RNGMNOXGNASE.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..434
FT                   /note="FAD-binding domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004685486"
FT   DOMAIN          6..195
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
FT   DOMAIN          316..350
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
SQ   SEQUENCE   434 AA;  46994 MW;  C627D048016D8F56 CRC64;
     MSSGNNVAII GAGLSGLTLA LALHQQGIQA TVYESRPAPS NIGGAVMLSP NALRVLDALS
     LYSVVKPQGY SFDRLDFRDG EGRVTETYEF GDAAKYGYQG LRIYRHVLID VLVAVLKEKG
     IPVVYGRTYS HVVREDGEDG GAVTFAFEDG TTETAALLVG ADGIHSTVRR HLYPDLQTTF
     LGMAGITAAV PTAQLRLPAD GSYHIPVTIA PRNKNKDASG GGASAFVIAP QQPDGSEVLI
     GKQRRILEHE RAAWEQRGSL ADGRAAAVAF LQEGSGPDNY PDIVANAVAA IDPAKVNVWP
     FYVVPKLERW ASAARRVILL GDAAHAIPPS AGQGINQAFE DVYMLALLLG WQSKQPKQAS
     GDGQAQAALD FWQQYRQARV DKVLELNRQI DLRRMPATDK AFATGVAREP FDLAWLYKPD
     FKKDVEDWVA QQTK
//