ID   U7PPX0_SPOS1            Unreviewed;       576 AA.
AC   U7PPX0;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   SubName: Full=Homoserine O-acetyltransferase {ECO:0000313|EMBL:ERS96966.1};
GN   ORFNames=HMPREF1624_06293 {ECO:0000313|EMBL:ERS96966.1};
OS   Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS   disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX   NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS96966.1, ECO:0000313|Proteomes:UP000018087};
RN   [1] {ECO:0000313|Proteomes:UP000018087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58251 / de Perez 2211183
RC   {ECO:0000313|Proteomes:UP000018087};
RX   PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA   Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA   Goldberg J., Young S., Zeng Q., Birren B.W.;
RT   "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT   58251).";
RL   Genome Announc. 2:E0044614-E0044614(2014).
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. MetX family.
CC       {ECO:0000256|ARBA:ARBA00006886}.
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DR   EMBL; KI440848; ERS96966.1; -; Genomic_DNA.
DR   AlphaFoldDB; U7PPX0; -.
DR   STRING; 1391915.U7PPX0; -.
DR   eggNOG; ENOG502QR3J; Eukaryota.
DR   HOGENOM; CLU_028760_7_0_1; -.
DR   OrthoDB; 63733at2759; -.
DR   Proteomes; UP000018087; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   HAMAP; MF_00296; MetX_acyltransf; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR008220; HAT_MetX-like.
DR   NCBIfam; TIGR01392; homoserO_Ac_trn; 1.
DR   PANTHER; PTHR32268; HOMOSERINE O-ACETYLTRANSFERASE; 1.
DR   PANTHER; PTHR32268:SF16; SERINE O-SUCCINYLTRANSFERASE; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW   Transferase {ECO:0000313|EMBL:ERS96966.1}.
FT   DOMAIN          164..535
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
FT   REGION          82..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          455..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        87..123
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   576 AA;  62604 MW;  35F1F0078D1A3E92 CRC64;
     MKAAQSLASA GMRSGTRLAV DGPSQIVRRS FCTQRPAAVR LFDVPSSQHS SRRSLHMTAA
     RCSGASNPAM AFPCLDALED RSQRLQSERQ QQQQQHQQTA TTETTKTTKS PRASESGPEP
     NYTSGATLRY HCEEPLRLDW GGVLREFDIA YETWGTLNAD RSNAILLHTG LSASSHAHST
     DINPEPGWWE KFIGPGEGFA LDTNKYFVIC TNVLGGCYGS TGPSSIDPAD GSHYATRFPI
     LTMEDMVRAQ FRLLDGLGVE RLYASVGSSM GGMQSLAAGV LFPDRVGKIV SISGCARSHP
     YSIAMRHTQR QVLMMDPNWN RGFYYGYGRV PPHAGMKLAR EIATVTYRSG PEWEQRFGRR
     RADPSKPPAL CPDFLIETYL DHAGEKFCLT YDPNSLLYVS KAMDLFDLGA AHQARSAQRR
     REREQKAAEA ASSVAGAGAG ADAVAAVCSL TLPDKPYEEQ PEAGQPSAAA AAAPPPPSDA
     DGHVASMMPG APSWQPPADL VQGLAVLRNH PTLVMGVASD ILFPAWQQYE VAEALKKAGN
     RNVSHYELSE QQSMFGHDTF LLDLKNIGGN VRNFLG
//