ID U7PVU5_SPOS1 Unreviewed; 530 AA.
AC U7PVU5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=HMPREF1624_03081 {ECO:0000313|EMBL:ERS99717.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS99717.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
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DR EMBL; KI440844; ERS99717.1; -; Genomic_DNA.
DR AlphaFoldDB; U7PVU5; -.
DR STRING; 1391915.U7PVU5; -.
DR eggNOG; KOG4628; Eukaryota.
DR HOGENOM; CLU_031409_1_0_1; -.
DR OrthoDB; 206729at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd16473; RING-H2_RNF103; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22765:SF453; FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G03900)-RELATED; 1.
DR PANTHER; PTHR22765; RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 90..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 329..371
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 37..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 54676 MW; 0AF41868F2D366C0 CRC64;
MPIIDLVLEG AALLARQATS TTATAITSAA TGTTGTIASA PTNGASLPGA SGAPATTTNP
PPAGTSGAPP SATTTSGGGG GGGGGGSSPL LFFVALGFGV VFTNLWIIVG VKYCFRYNAR
ARQLRLAAED GEPINLENMP HPRRRRREKK LMTIDEVNEK FPMLKYKTWV ATRAEEGLPT
TGGIDAPSRA NSVRSAEGVI ASVDETERRQ RRASTDEPED SHDKERPPTS IAEAGTSVHD
STTADGAAAA AASATTDAAP DAPSTSTAPN FTTMDITRAS LASADGDVGL GVYNKDSLPE
HYNHSDDEDD EHIDSALPPE CVGTSGDTCA ICIDTLEDDD DVRGLTCGHA FHAVCLDPWL
TSRRACCPLC KADYYTPKPR PPPAEGADAA NAQGAAAAAA VAADRNRAIM QARPGTSWRS
AILPSRFMPG SRNANAQDAE RVSPQRETNE PNANASANAN AAPAAAASEV QPLPEQPAPT
HGGWLRSFRQ RNGESSQEQA PAAAAGNAAE PAAPAAEVTP SQLEAGVRAR
//
