ID U7PX57_SPOS1 Unreviewed; 631 AA.
AC U7PX57;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Calcineurin-like phosphoesterase domain-containing protein {ECO:0000259|Pfam:PF00149};
GN ORFNames=HMPREF1624_04703 {ECO:0000313|EMBL:ERS99501.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERS99501.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
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DR EMBL; KI440845; ERS99501.1; -; Genomic_DNA.
DR AlphaFoldDB; U7PX57; -.
DR STRING; 1391915.U7PX57; -.
DR eggNOG; KOG4419; Eukaryota.
DR HOGENOM; CLU_019028_0_0_1; -.
DR OrthoDB; 5490776at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR CDD; cd07407; MPP_YHR202W_N; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 2.
DR InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR InterPro; IPR006179; 5_nucleotidase/apyrase.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR014485; Pesterase_C1039.
DR InterPro; IPR041823; YHR202W_N.
DR PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR PANTHER; PTHR11575:SF43; SER_THR PROTEIN PHOSPHATASE FAMILY (AFU_ORTHOLOGUE AFUA_3G04160); 1.
DR Pfam; PF00149; Metallophos; 1.
DR PIRSF; PIRSF017316; Pesterase_C1039; 1.
DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018087}.
FT DOMAIN 10..235
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT REGION 491..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 70463 MW; D7201068B00A8E99 CRC64;
MRPLQWGQIN FLHTTDTHGW HAGHLQESQY SADWGDYISF ADHMRQRADK EGVDLLLVDT
GDRVEGNGLY DASTPKGQYT YDIFRQQDID IICSGNHELY QADTADREHH QTVPNFAGHY
LASNLDYIDP KTGKQVPMSE QRYRTFQTKH QKLNIVAFGF LFNFTANAAN SVVQPVQKTM
QEPWFKHAIT NEPADLFVVI GHVGARMGEL RVIYEAIRAA NEHTPIAIFA GHAHARDAVR
FDDRAVAIAS GRYLETIGWM SVTGVKAEAP APITFARRYI DNNLLGLYYH SGTNATTFPT
DHGLNVTATI AAARSDLDLE TPYGCAPQNY WLQRRPHDDP ASVFSLLRKH VLPEAIVRPD
RADVPRLVLI NTGAMRFDIF RGAFTRDTTF IVSPFISLVR YIPDVPYALA RQVLPILNHF
GPILSAMAAE ARAAGVTDES EAWAGVTDWR EMGVPEAYSL REEDNAHIIG ADGGIKDSGH
DAAQQKPLFG RRAETAAASR SSSDDDASRP PLVAGYTTWD DFGFDGDDAV HEPLPHFRLP
NCIQAEASFP KAATWTEELA EPATVDFVFF DFIQRFVLQA LAYAEQNAGG VAPDGTPYKH
YTDADVEAYL ENKFTDYFAD WVKRNWGDEC T
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