ID   U7Q120_SPOS1            Unreviewed;      1228 AA.
AC   U7Q120;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Pentacotripeptide-repeat region of PRORP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF1624_02105 {ECO:0000313|EMBL:ERT00872.1};
OS   Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS   disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX   NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT00872.1, ECO:0000313|Proteomes:UP000018087};
RN   [1] {ECO:0000313|Proteomes:UP000018087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58251 / de Perez 2211183
RC   {ECO:0000313|Proteomes:UP000018087};
RX   PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA   Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA   Goldberg J., Young S., Zeng Q., Birren B.W.;
RT   "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT   58251).";
RL   Genome Announc. 2:E0044614-E0044614(2014).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI440843; ERT00872.1; -; Genomic_DNA.
DR   AlphaFoldDB; U7Q120; -.
DR   STRING; 1391915.U7Q120; -.
DR   eggNOG; KOG4197; Eukaryota.
DR   HOGENOM; CLU_002863_0_0_1; -.
DR   OrthoDB; 2056457at2759; -.
DR   Proteomes; UP000018087; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR   InterPro; IPR002885; Pentatricopeptide_rpt.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   NCBIfam; TIGR00756; PPR; 3.
DR   PANTHER; PTHR45613:SF476; MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1; 1.
DR   PANTHER; PTHR45613; PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN; 1.
DR   Pfam; PF13041; PPR_2; 1.
DR   Pfam; PF13812; PPR_3; 1.
DR   PROSITE; PS51375; PPR; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018087}.
FT   REPEAT          417..451
FT                   /note="PPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT   REPEAT          915..949
FT                   /note="PPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT   REPEAT          950..980
FT                   /note="PPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT   REGION          240..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        245..260
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1228 AA;  133836 MW;  8844B3E53AA1DCEB CRC64;
     MPTIYSSLYQ TFIRQGFAKS FTHGYAQSVV AATHPHVLNP QNRPSFARRN CNRFGRIQAL
     QLQSAFHTQT SGPDHKQLSL NHGGLDAYFE HLQDLQAQDE TDKEWVQFQF QNRIEWKPSA
     ASVLDNEEVS AKAAEADVGV DAAAAEEASA EFIVALGEEG GLASEQVGEQ DVAAAADTAS
     AVEAVAVEDV LADRHSAAEE AALAHIDAAL EKEIEARKNL EALEDGKVAS TSPVAAGEVA
     KSRSVPVSRS RSPVRSVSPV VDKQSQTYAD HLATLSESGR YTEIPAVFEA MLVAGVRPIA
     SAYNALLMAA IHLPIDRMEV ISKALDVYTD MIRRKVLPDS DTFNILVGLL ASRSLELAAK
     KTLLEEKRLR YGGMDEPGKF MFASHELEHA IAAEEDRLDY AIKLFENSVA AQKAAYSSET
     YHQLISACAQ SGRLSDMLQL FGHMEANKIA PFAATFPAMI TAFANAGDLI SAVECYEEYR
     NLAIANDAGE PSLLDRLDTQ VYAAVINAYI TCDKMPGAMK FFDKINEQYG VRAANMKDAL
     INDGFVQGFT SRGHYATALE WVQNVDKATQ AQTLGKIATV AADNGHKDLA VAAFDALTNA
     FPSALSSMAG PTTALLALYV RAGDVAAASK YWHILRNPLV EVSSSFIEPT AMYAVAMIGS
     GQVAEALVES DIMFDRIRQS AEARTHAAIV DEIEEGVAFI NRFMQARGVT DPREDASSAA
     SFVPPASSFV SSPFPSTPTV SSFDETSNFD PYAHNTDYKG SSLISDDLEG SHGRKGPKLN
     EALNRFRNMR RAGRHPRYIT YAKLISAASR ENKMDLCHNI LAMARADVPL LPQYAVVRYG
     WSSILDAMIG ASLSVGNRTL AEQYHQELLS FGSAPSANTF GLYITTLKES TKTFDEASEA
     VKIFHRAKAE GVEPSSFLYN ALIGKLGKAR RIDDCLFYFA EMRALSIKPT SVTYGTIVNA
     LCRVSDDKFA EELFDEMEAM PNYKARPAPY NSMMQFFLTT KRDKAKVLAY YERMLARGIA
     PTSHTYKLLV DTHATLEPVN MTAAEAVLDR IRAAGQTPEA VHYASLIHAR GCNMHDMEGA
     RRIFDSVMKD KSVSANACLF QALFEAMVAN HQVADTEPIL AMMRERRIDI TPYIANTLIH
     GWAAEKDIAK AVSIYSSVGR ERREPSTYEA MTRAFLAVEE RDKAQGVVSE MLHRGYPSAV
     VNKVLELLGG GAGHADEAAA TVAAPVAA
//