ID U7Q3E3_SPOS1 Unreviewed; 512 AA.
AC U7Q3E3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=3-phytase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1624_00006 {ECO:0000313|EMBL:ERT01712.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT01712.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI440842; ERT01712.1; -; Genomic_DNA.
DR AlphaFoldDB; U7Q3E3; -.
DR STRING; 1391915.U7Q3E3; -.
DR eggNOG; KOG1382; Eukaryota.
DR HOGENOM; CLU_020880_3_0_1; -.
DR OrthoDB; 2404758at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR CDD; cd07061; HP_HAP_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR000560; His_Pase_clade-2.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR016274; Histidine_acid_Pase_euk.
DR PANTHER; PTHR20963:SF23; 3-PHYTASE; 1.
DR PANTHER; PTHR20963; MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED; 1.
DR Pfam; PF00328; His_Phos_2; 1.
DR PIRSF; PIRSF000894; Acid_phosphatase; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR000894-2};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..512
FT /note="3-phytase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004686055"
FT ACT_SITE 77
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-1"
FT ACT_SITE 349
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-1"
FT DISULFID 66..398
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
FT DISULFID 261..275
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
FT DISULFID 451..459
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
SQ SEQUENCE 512 AA; 55048 MW; C7CFFE356F930801 CRC64;
MALLASVLVL ASAANAQVGS MLSPAFDINF LKTSAASNPL GWLGANGPYA SGPNVYGISS
DVPEHCTVDQ AFFVSRHASR YPDPGAYNGW VDMKNRFSAG NGYNATGTLS FLPSWKPVLT
NSGLQMSNLS PTGQKEAFDM AYALRTKYPQ LYNEGDDLYV WANNYSRVLQ TAKLFVRGFL
GVNATNLGHI VSVTSSGSVD AIGNSLGPSD SCPNFVDVSG GMYFSNWSNV YIPPIQKRLQ
SLISGNLTFT SDDISQIPYL CGFESQITGR LSPWCNVFSD KELQYYQYSN DLRYYYGVGP
GTKLPATMML PYLNAVMGLL KTGPGALHGT AADGSDFTVP QLLVSFLNDG QLNELITASG
VHDAQAALSD SHMDPNRLYI GNRFTTMRGT VGFERLNCAV RPSRNSSSDL LPLAQRTCGG
NTKVPSFPPS ITNHTFIRVL LNDAVYPVPG CQNGPGYSCL LDDYVEFVGS KYNKSGNWAE
NCGVTAPGAP KVVAGATFYT KLGGDFLQVI SP
//
