ID   U7Q5X5_SPOS1            Unreviewed;      1475 AA.
AC   U7Q5X5;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   13-SEP-2023, entry version 36.
DE   RecName: Full=Tubulin-specific chaperone D C-terminal domain-containing protein {ECO:0000259|Pfam:PF12612};
GN   ORFNames=HMPREF1624_00882 {ECO:0000313|EMBL:ERT02582.1};
OS   Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS   disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX   NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT02582.1, ECO:0000313|Proteomes:UP000018087};
RN   [1] {ECO:0000313|Proteomes:UP000018087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58251 / de Perez 2211183
RC   {ECO:0000313|Proteomes:UP000018087};
RX   PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA   Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA   Goldberg J., Young S., Zeng Q., Birren B.W.;
RT   "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT   58251).";
RL   Genome Announc. 2:E0044614-E0044614(2014).
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DR   EMBL; KI440842; ERT02582.1; -; Genomic_DNA.
DR   AlphaFoldDB; U7Q5X5; -.
DR   STRING; 1391915.U7Q5X5; -.
DR   eggNOG; KOG1943; Eukaryota.
DR   HOGENOM; CLU_003043_3_0_1; -.
DR   OrthoDB; 5477080at2759; -.
DR   Proteomes; UP000018087; Unassembled WGS sequence.
DR   GO; GO:0048487; F:beta-tubulin binding; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IEA:InterPro.
DR   GO; GO:0007021; P:tubulin complex assembly; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR033162; TBCD.
DR   InterPro; IPR022577; Tubulin_specific_chaperoneD_C.
DR   PANTHER; PTHR12658; BETA-TUBULIN COFACTOR D; 1.
DR   PANTHER; PTHR12658:SF0; TUBULIN-SPECIFIC CHAPERONE D; 1.
DR   Pfam; PF12612; TFCD_C; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018087}.
FT   DOMAIN          1139..1327
FT                   /note="Tubulin-specific chaperone D C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12612"
FT   REGION          187..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          243..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1475 AA;  154544 MW;  7CC913D21FC15E0A CRC64;
     MDANDEDDDV RLQRIAGDLL SDFDGSLESF LFKPAPAVTA YGSTKTKGRR VRARVRSRET
     ARMANLLEHF QELPQLLDVH LARWLPMLAD AFLQSVECNS KCSAKANATA AAATAAAFAE
     AATTSHGGAG SSSSTSSLVM PLQAAVARLL YTVCKVRGEK VVVGFLPVET RHLEPLLGAL
     EAQAADISGQ PHSNVRSSTS NSGNDGRDGN EHGSWTWQER YLVLLWLSQL LLAPFDLSTI
     STGRRGQVAD EDDEEAGEEG GSGSKHSRLP AIDGFTWPGV DATTTPIAIP SITLRVLPLA
     VRYLAVPGKE RDAARALLVR IAMRRDMQEL GVRQALVHWA LGSLDGRAPT IHQPYYYIGT
     LSFLAGILSA AAGASDMDDA LASIFAAVNA VADEDGPEAA NAVFAAVRSS ALARKMMIKA
     SRAVAVRYIQ LLDQLGARGP DTNPGLVEAA DVAIETTIGY LLGRLADNDT PVRFAASKAL
     SIITLRLRPD MAAQVSDAVL EALERNVVAQ NGKLDLTAVD PLEWHGLMLT LAHLIYRRSP
     PLDALPAIVR ALQRGLAFER RSVSGSATGT NVRDAACFGI WALARRYTTA ELLPLNVLQT
     LATDLVVAGS LDPAGNIRRG SSAALQELIG RHPDIICEGI PLVQAVDYHA VALRSRAVTD
     VAQRATALAH SMYGVALRDA LLGWRGFADA GDAGARRTAA QSFGQVTLLM AMAEKGRGPG
     TSPLDYFAAS VRTLVGRVES LQTRQVEERH GFLLALAAVL DSFPSLVETA RETEGESSKL
     TELCLSVLDL LHQVLHKCKA LSAARRPDLL AEAASRLIVS SFPIVQAAVV LRGGFDWTQG
     SRSLALLSGP ALLAEANLLP ATLFHKTVVA LDSAFASDPR PDPDSASSTT PHTALQAFVN
     LAAACLSGPN AWLGRQEIDV IAAASDAALI VLVALGPSPV APSVPSTSTP SEPPVPPTRD
     SLVSFWSSVV CRPKAAAAVS FKARASGSGT TGTGYVFALT KAFSLYEISR TTATPEGSAT
     GDGDPISRAL LGRWAADRSI DTRIALLQAL AQCPAVLMQR ATTASSVSSA SVTPAAPGSR
     FRSILAAGLD DYTTDARGDV GSHVRMHALR ATQVLWSQEA VLGAGATPKP AGASILFYRV
     LRLAAEKLDR VRIAAQATLA QALGGERSTY LQSLPFSSQA YFRCLLGLWE DVADGEGGSN
     ILSSSTSSIA AAAAKSGDGA SPSLASAATK WMAALMRGYV TSADTGNEEL VVASRAAMVD
     YIVNSGGGQQ QRQSRQQCLW QALLRNMPGS RAAATTAAGK AITPPDRIVV PTLEIIAFLF
     NAGVFLPPVS TGSNATTTPC HADLLDLSRQ VNEAVEKAGS VRKVEACVKV YGAVAAASDR
     AGSSVTVENN AAGTVARAKL ADLLQHPWPR VRNAVVDELW GLGLGQGLGV SLDTAAGAGA
     GPDSGPAAFD VLKGVDWVAA DTAALQALAG ELGLV
//