ID U7Q6L6_SPOS1 Unreviewed; 589 AA.
AC U7Q6L6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE RecName: Full=DNA primase {ECO:0000256|RuleBase:RU003514};
DE EC=2.7.7.- {ECO:0000256|RuleBase:RU003514};
GN ORFNames=HMPREF1624_00976 {ECO:0000313|EMBL:ERT02675.1};
OS Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT02675.1, ECO:0000313|Proteomes:UP000018087};
RN [1] {ECO:0000313|Proteomes:UP000018087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58251 / de Perez 2211183
RC {ECO:0000313|Proteomes:UP000018087};
RX PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA Goldberg J., Young S., Zeng Q., Birren B.W.;
RT "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT 58251).";
RL Genome Announc. 2:E0044614-E0044614(2014).
CC -!- SIMILARITY: Belongs to the eukaryotic-type primase small subunit
CC family. {ECO:0000256|ARBA:ARBA00009762, ECO:0000256|RuleBase:RU003514}.
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DR EMBL; KI440842; ERT02675.1; -; Genomic_DNA.
DR AlphaFoldDB; U7Q6L6; -.
DR STRING; 1391915.U7Q6L6; -.
DR eggNOG; KOG2851; Eukaryota.
DR HOGENOM; CLU_028288_1_0_1; -.
DR OrthoDB; 168741at2759; -.
DR Proteomes; UP000018087; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003896; F:DNA primase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04860; AE_Prim_S; 1.
DR Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR InterPro; IPR002755; DNA_primase_S.
DR InterPro; IPR014052; DNA_primase_ssu_euk/arc.
DR NCBIfam; TIGR00335; primase_sml; 1.
DR PANTHER; PTHR10536; DNA PRIMASE SMALL SUBUNIT; 1.
DR PANTHER; PTHR10536:SF0; DNA PRIMASE SMALL SUBUNIT; 1.
DR Pfam; PF01896; DNA_primase_S; 1.
DR SUPFAM; SSF56747; Prim-pol domain; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU003514};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU003514};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Primosome {ECO:0000256|ARBA:ARBA00022515, ECO:0000256|RuleBase:RU003514};
KW Reference proteome {ECO:0000313|Proteomes:UP000018087};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003514}.
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 521..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 589 AA; 65906 MW; 02B35682C359FAA5 CRC64;
MPHAVSDPPS PTQDDAAMAE NASPNTIEAE SPPTANANVG DEAVPVKVEQ ASSPPWVAGD
DDDDDDIDVE MTEESAVPAA AVAIKTEDGP AEGVLAATTA IKTEDAPAAA VVKTEESEKA
ALITDMVPVN LEDMFDDMDD DEFSGKSAED ALATTSDLLS LRASDPEVMR SFYQRLFPWR
YLFQWLNHSP TPTNDFAHRE FAFTLQNDAY LRYQAFPTSD LLRKDVLRLL PSRFEIGPVY
TTNPVDRKAL SNASAFKPLA KELCFDIDLT DYDDIRTCCD KTTICIRCWQ FITMAVRVID
VALRDDFGFQ HIVWIYSGRR GAHAWVCDKR ARTLDDQRRR AIVGYLEVLR GGSQGGKRVN
VRRPLHPHLS RSLNELRTHF QEDVLRDQDP WATAENAEKL LGLLSDRNLA DALRRKWDSS
PGRSSTAKWA DIDAVAKTGS VKGLDMKQLL ENKQDIVLEY TYPRLDVNVS KKLNHLLKSP
FVVHPGTGRV CVPIDVDRLE EFDPLGVPTV QQLLQEIDSY QQNGTGASGS DEEPSQGNNG
DEKKLQDWEK TSLRPYIEQF RSFVLALMRD EKDVVRVKRE RDGATSMEF
//
