ID U7QJ70_9CYAN Unreviewed; 616 AA.
AC U7QJ70;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Precorrin-3B C17-methyltransferase {ECO:0000313|EMBL:ERT08004.1};
DE EC=2.1.1.131 {ECO:0000313|EMBL:ERT08004.1};
GN Name=cobJ {ECO:0000313|EMBL:ERT08004.1};
GN ORFNames=M595_1979 {ECO:0000313|EMBL:ERT08004.1};
OS Lyngbya aestuarii BL J.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Lyngbya.
OX NCBI_TaxID=1348334 {ECO:0000313|EMBL:ERT08004.1, ECO:0000313|Proteomes:UP000017127};
RN [1] {ECO:0000313|EMBL:ERT08004.1, ECO:0000313|Proteomes:UP000017127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BL J {ECO:0000313|EMBL:ERT08004.1,
RC ECO:0000313|Proteomes:UP000017127};
RX PubMed=24376438; DOI=10.3389/fmicb.2013.00363;
RA Kothari A., Vaughn M., Garcia-Pichel F.;
RT "Comparative genomic analyses of the cyanobacterium, Lyngbya aestuarii BL
RT J, a powerful hydrogen producer.";
RL Front. Microbiol. 4:363-363(2013).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERT08004.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AUZM01000015; ERT08004.1; -; Genomic_DNA.
DR AlphaFoldDB; U7QJ70; -.
DR PATRIC; fig|1348334.3.peg.1928; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000017127; Unassembled WGS sequence.
DR GO; GO:0030789; F:precorrin-3B C17-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR Gene3D; 3.40.50.11220; -; 1.
DR Gene3D; 3.30.420.180; CobE/GbiG C-terminal domain; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR021745; CbiG_mid.
DR InterPro; IPR021744; CbiG_N.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR002750; CobE/GbiG_C.
DR InterPro; IPR036518; CobE/GbiG_C_sf.
DR InterPro; IPR038029; GbiG_N_sf.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF01890; CbiG_C; 1.
DR Pfam; PF11761; CbiG_mid; 1.
DR Pfam; PF11760; CbiG_N; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF159672; CbiG N-terminal domain-like; 1.
DR SUPFAM; SSF159664; CobE/GbiG C-terminal domain-like; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ERT08004.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ERT08004.1}.
FT DOMAIN 53..131
FT /note="Cobalamin synthesis G N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11760"
FT DOMAIN 138..223
FT /note="Cobalamin biosynthesis central region"
FT /evidence="ECO:0000259|Pfam:PF11761"
FT DOMAIN 226..357
FT /note="CobE/GbiG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01890"
FT DOMAIN 370..580
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 616 AA; 66883 MW; 5C6340AA2375F40B CRC64;
MIAFEPIAAI ATTPHACQRL QPLCQTAEVT LYVPQSLGNI PKTQVYPDSL RQLLPQLWSS
HRAIVFCLAL GAVVRLIAPL LQHKSTDPAI IVVDETGQFV ISVCSGHIGG GDRLAQLVAR
ILGATPILTG SANALNLPGI DILGVPFGWK RGSGDWTGVS AAIAQQQTVQ VRQEAGSTLW
QHHLPATHSF DFTSTQTPQA QIWISPQHRQ LSTEDLPQVQ WHPRVLWVGV GCERNTPKAV
IETAILDVLR AHQLAEEAVA GIASLDLKAD ETGLVELCQA RHWPLQTFSA EILRQVTVPT
PSEIVQSEVG TPSVAEAAAL QAAQVQALLV SKQIYRSPQP QPSEAERIGQ AVTVAIAIAQ
QEYTGRDGQL LLVGTGPGQL NQMTPAAQTA VTQADVVIGY SLYLDLITPL LRPGQIVESY
PITQERQRAE RAIELAEWGL TVAVVSSGDC GIYGMAGLVF EQLRAQGWRG ETPGVQVFPG
ISALQAAASR VGAPLMHDFC AISLSDLLTP WEMIEKRLKA AAMADFVCAL YNPRSRSRTE
QLSQAQMIFL QFRSPQTPVA LVRSAYRDDE QITLTTLEEL TEVSVDMLTT VLIGNQSTTF
HQNWMITPRG YLGFTQ
//
