ID U7QJN5_9CYAN Unreviewed; 736 AA.
AC U7QJN5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=M595_3417 {ECO:0000313|EMBL:ERT06636.1};
OS Lyngbya aestuarii BL J.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Lyngbya.
OX NCBI_TaxID=1348334 {ECO:0000313|EMBL:ERT06636.1, ECO:0000313|Proteomes:UP000017127};
RN [1] {ECO:0000313|EMBL:ERT06636.1, ECO:0000313|Proteomes:UP000017127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BL J {ECO:0000313|EMBL:ERT06636.1,
RC ECO:0000313|Proteomes:UP000017127};
RX PubMed=24376438; DOI=10.3389/fmicb.2013.00363;
RA Kothari A., Vaughn M., Garcia-Pichel F.;
RT "Comparative genomic analyses of the cyanobacterium, Lyngbya aestuarii BL
RT J, a powerful hydrogen producer.";
RL Front. Microbiol. 4:363-363(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERT06636.1}.
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DR EMBL; AUZM01000033; ERT06636.1; -; Genomic_DNA.
DR RefSeq; WP_023067143.1; NZ_AUZM01000033.1.
DR AlphaFoldDB; U7QJN5; -.
DR PATRIC; fig|1348334.3.peg.3305; -.
DR Proteomes; UP000017127; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF32; DRUG SENSORY PROTEIN A; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 219..271
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 280..334
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 454..712
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 736 AA; 82699 MW; 56E5D3E953AEE60F CRC64;
MIAILKKIGE IIANWWSEFT LQTRLMAGAT LVVSLLMSGL TFWAVNAIQE DARLNDTRYG
RDLGLLLAAN VAPLIADNKR DEVARFSRQF YTSTSSVRYM LYADPDGEIF LGLPFSDSAV
QNSLTLRRRM QLPDNFITSI KAGDFTSIPM VRQHMTPAGQ VTDVFVPLMD EGQYWGILAI
GINPNPTVVV SSNLTRDVTL AVFVSIWVMV ILGAVFNALT ITQPIKELLR GVQNITAGNF
HQRVDLPFGG ELGELIISFN KMAERLESYE AQNIEELTAE KAKLETLVLT IADGAILLDA
QLNLILVNPT ARRLFNWDGK SVIGENAINH FPLPLLQEIS QPLQQIASGN QEGGEFRCSL
SEPTNRTLRI LLNTVLLHKA PGLDPLCGSC FSHTNETCNS PEHPQANESS LYQHHDHLKL
EDQYRDSLKG IAMTIQDITR EVELNEAKSY FISNVSHELR TPLFNIKSFI ETLHDYGEDL
TEAERREFLE TANYETDRLT RLVNDVLDLS RLESCRIYHF EGIDIAQPIE QTLRTYQLNA
KDKGIELSQE VEPDLPPVLG HYDLLLQVFA NLVGNSLKFT QAGGRVIIRA YLLEDDQPKV
ISKEAEEIEK GGWIISPPPP RPLDEKIGLE IPSSPQYVRI EVSDTGSGIA AEDQEAVFSR
FYRVENRVHT LEGTGLGLSI VRNIMEKHHS QIHLISELGI GTTFWFDLAV YQDFQDFQAH
TKEIEYINKS LPNNNN
//
