ID U7U795_9BURK Unreviewed; 629 AA.
AC U7U795;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Sulfatase {ECO:0000313|EMBL:ERT55146.1};
GN ORFNames=N879_14800 {ECO:0000313|EMBL:ERT55146.1};
OS Alcaligenes sp. EGD-AK7.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Alcaligenes.
OX NCBI_TaxID=1386079 {ECO:0000313|EMBL:ERT55146.1, ECO:0000313|Proteomes:UP000016497};
RN [1] {ECO:0000313|EMBL:ERT55146.1, ECO:0000313|Proteomes:UP000016497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EGD-AK7 {ECO:0000313|EMBL:ERT55146.1};
RX PubMed=24407646;
RA Sagarkar S., Bhardwaj P., Yadav T.C., Qureshi A., Khardenavis A.,
RA Purohit H.J., Kapley A.;
RT "Draft genome sequence of atrazine-utilizing bacteria isolated from Indian
RT agricultural soil.";
RL Genome Announc. 2:e01149-13(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERT55146.1}.
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DR EMBL; AVOG02000067; ERT55146.1; -; Genomic_DNA.
DR RefSeq; WP_022983504.1; NZ_AVOG02000067.1.
DR AlphaFoldDB; U7U795; -.
DR OrthoDB; 9760224at2; -.
DR Proteomes; UP000016497; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.30.1120.80; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000016497};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 269..536
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 316
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 277
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 432
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 485
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 486
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 629 AA; 70690 MW; 40A71C8BF38CC2F2 CRC64;
MRHLVYVFVP SALILLTAFR LAFALWQWPR VRQAGGLLPI LIGGLRIDAL MIAALSAPVV
LLAPWLGHYP VMTTIAAIWF TFAWFLLTLL EVSTPQFIIE YDTRPNRLYV DYLKHPQEVV
GMLWKGYKLM IGIALIGLGL IVYSGWSIFG HVSADPVMSW WLRPIWMLIA AALCILAIRG
TLAHRPINPS SVAWSSDSML NTLPLNSLYN VAYAIYSMKN ERSAEDIYGG LDVAEMNQIV
RDAAALPAGP DTLPTLHRQT PVQKRERKPN LVLIVEESLG AQYVSNLGGA NLTPELDKLA
QTGWNFRRAY ATGTRSVRGL EAVSAGFPPT VADAVLRLPG SQTRFFTLAQ LLKEQGYRSR
FIYGGEAHFD NMKSFFLGNG FDELHEQSSF ESPEFVGTWG ASDEDMFNKL HQLLSQDKEQ
PTLTLAFSVS NHSPWEYPAG RIQVEGDPAT VENTVRYADW AIGDFFKKAR ESDYWDNTVF
LIVADHDSRV GGANLVPVRH FHIPALILGA GVPSRQDERI MSQIDLAPTL LSLMGIESEH
PMIGRDLTQQ DSDRAMMQYF ENYGYLKGDI LTVLMPHLPP CQYRYTAPDK YEPLEQIDEG
LAKEALAHVL WPSWAYHEQA YTLPHLQKR
//
