ID UFOG7_MANES Reviewed; 287 AA.
AC Q40289;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE RecName: Full=Anthocyanidin 3-O-glucosyltransferase 7;
DE EC=2.4.1.115;
DE AltName: Full=Flavonol 3-O-glucosyltransferase 7;
DE AltName: Full=UDP-glucose flavonoid 3-O-glucosyltransferase 7;
DE Flags: Fragment;
GN Name=GT7; Synonyms=UGT73A7;
OS Manihot esculenta (Cassava) (Jatropha manihot).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae;
OC Manihot.
OX NCBI_TaxID=3983;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Cotyledon;
RX PubMed=7894058; DOI=10.3109/10425179409039703;
RA Hughes J., Hughes M.A.;
RT "Multiple secondary plant product UDP-glucose glucosyltransferase genes
RT expressed in cassava (Manihot esculenta Crantz) cotyledons.";
RL DNA Seq. 5:41-49(1994).
CC -!- FUNCTION: In the presence of other necessary color factors, this
CC glycosylation reaction allows the accumulation of anthocyanin pigments.
CC {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an anthocyanidin + H(+) + UDP-alpha-D-glucose = an
CC anthocyanidin 3-O-beta-D-glucoside + UDP; Xref=Rhea:RHEA:20093,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16307, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:58885, ChEBI:CHEBI:143576; EC=2.4.1.115;
CC -!- PATHWAY: Pigment biosynthesis; anthocyanin biosynthesis.
CC -!- TISSUE SPECIFICITY: Expressed in cotyledons, hypocotyls, roots and
CC leaves.
CC -!- DEVELOPMENTAL STAGE: Expressed in all tissues (cotyledon, hypocotyls
CC and roots) at uniform levels at all stages of development.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X77464; CAA54614.1; -; mRNA.
DR PIR; S41953; S41953.
DR AlphaFoldDB; Q40289; -.
DR SMR; Q40289; -.
DR CAZy; GT1; Glycosyltransferase Family 1.
DR EnsemblPlants; OAY44585; OAY44585; MANES_08G163200.
DR Gramene; OAY44585; OAY44585; MANES_08G163200.
DR UniPathway; UPA00009; -.
DR GO; GO:0047213; F:anthocyanidin 3-O-glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009718; P:anthocyanin-containing compound biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48049:SF29; FLAVONOL 3-O-GLUCOSYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR48049; GLYCOSYLTRANSFERASE; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase; Transferase.
FT CHAIN <1..287
FT /note="Anthocyanidin 3-O-glucosyltransferase 7"
FT /id="PRO_0000074148"
FT BINDING 162
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT BINDING 164
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT BINDING 179
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT BINDING 182
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT BINDING 183
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT BINDING 184
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT BINDING 187
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT BINDING 202
FT /ligand="an anthocyanidin"
FT /ligand_id="ChEBI:CHEBI:143576"
FT /evidence="ECO:0000250|UniProtKB:P51094"
FT BINDING 203
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT BINDING 204
FT /ligand="UDP-alpha-D-glucose"
FT /ligand_id="ChEBI:CHEBI:58885"
FT /evidence="ECO:0000250|UniProtKB:A0A0A1HA03"
FT NON_TER 1
SQ SEQUENCE 287 AA; 31397 MW; 0A0D9C153C193571 CRC64;
TLNLIPGMSK IQIRDLPEGV LFGNLESLFS QMLHNMGRML PRAAAVLMNS FEELDPTIVS
DLNSKFNNIL CIGPFNLVSP PPPVPDTYGC MAWLDKQKPA SVAYISFGSV ATPPPHELVA
LAEALEASKV PFLWSLKDHS KVHLPNGFLD RTKSHGIVLS WAPQVEILEH AALGVFVTHC
GWNSILESIV GGVPMICRPF FGDQRLNGRM VEDVWEIGLL MDGGVLTKNG AIDGLNQILL
QGKGKKMREN IKRLKELAKG ATEPKGSSSK SFTELANLVR SRGSYEN
//
