ID   V2WNL0_MONRO            Unreviewed;       643 AA.
AC   V2WNL0;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=Reverse transcriptase-rnase h-integrase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=Moror_16779 {ECO:0000313|EMBL:ESK81800.1};
OS   Moniliophthora roreri (strain MCA 2997) (Cocoa frosty pod rot fungus)
OS   (Crinipellis roreri).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX   NCBI_TaxID=1381753 {ECO:0000313|EMBL:ESK81800.1, ECO:0000313|Proteomes:UP000017559};
RN   [1] {ECO:0000313|EMBL:ESK81800.1, ECO:0000313|Proteomes:UP000017559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MCA 2997 {ECO:0000313|EMBL:ESK81800.1,
RC   ECO:0000313|Proteomes:UP000017559};
RX   PubMed=24571091; DOI=10.1186/1471-2164-15-164;
RA   Meinhardt L.W., Costa G.G.L., Thomazella D.P.T., Teixeira P.J.P.L.,
RA   Carazzolle M.F., Schuster S.C., Carlson J.E., Guiltinan M.J.,
RA   Mieczkowski P., Farmer A., Ramaraj T., Crozier J., Davis R.E., Shao J.,
RA   Melnick R.L., Pereira G.A.G., Bailey B.A.;
RT   "Genome and secretome analysis of the hemibiotrophic fungal pathogen,
RT   Moniliophthora roreri, which causes frosty pod rot disease of cacao:
RT   mechanisms of the biotrophic and necrotrophic phases.";
RL   BMC Genomics 15:164-164(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESK81800.1}.
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DR   EMBL; AWSO01002226; ESK81800.1; -; Genomic_DNA.
DR   RefSeq; XP_007858894.1; XM_007860703.1.
DR   AlphaFoldDB; V2WNL0; -.
DR   KEGG; mrr:Moror_16779; -.
DR   HOGENOM; CLU_000384_6_12_1; -.
DR   OrthoDB; 1606426at2759; -.
DR   Proteomes; UP000017559; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 2.40.50.40; -; 1.
DR   Gene3D; 3.10.20.370; -; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR   InterPro; IPR023780; Chromo_domain.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR45835:SF106; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45835; YALI0A06105P; 1.
DR   Pfam; PF00385; Chromo; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   SMART; SM00298; CHROMO; 1.
DR   SUPFAM; SSF54160; Chromo domain-like; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50013; CHROMO_2; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017559};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW   Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT   DOMAIN          287..447
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   DOMAIN          586..643
FT                   /note="Chromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50013"
SQ   SEQUENCE   643 AA;  74058 MW;  3EAC56A92CBD07AE CRC64;
     MPDDEKPFII EADASKWATG AVLKQQGSDG ELHPCGYISH TFTATERNYE IYDRELLAIT
     NALKAWEHYL LGGAHPVTVL SDHKNLTYFR TAQKLNRRQA RLSLYLTQFD LRLVHVPGMK
     MVQSDALSRQ PDLVDEEEND NDDIVMLPDK LFVNVIDAEL KTILEDALPR DEFLQMTMES
     LIEKGTPPIK SSLQDWRTEG NLLFYKDRIY VPNDLTLQRL VVKTIHKALP HGHPGQWNTV
     DQVQRDYWWP GMTKFIKSFV DGCAACQQMK VNTHPTQMPI QPIGGHKDAL PFQIILMDLI
     TDLPKVDESD LILVVVDHAA TKGVIFIPCH KKINATDTAE LLFQHVYKHF GLPDKIISDR
     DPQFAAEVFK EMGKLLGIKQ MLSTAYHPQT DGETERVNQE VEIFLRFFCA KEQTKWKDLL
     HFAEFAHNTQ MHSVTKNSPF YLTMGYHPRP LPTVFEKTTI PSVEKRVAEL KKLREETSAL
     LDIAARRVKE RSGKDLDEFE KGQKVWLEGK NLSLGYPSPK LSPKREGPFE ITEVLGPVTY
     KLKLPFQWRI HPVFHANLLS PYKETDVHGP NFLEPPPDIV EGQEEYEVEA IIGHRPKRKN
     QPPKEYLVSW KGYDSSHNQW LKPAGLKHLM ELYLDYKIKY NLR
//