ID V2WNV0_MONRO Unreviewed; 762 AA.
AC V2WNV0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Reverse transcriptase-rnase h-integrase {ECO:0008006|Google:ProtNLM};
GN ORFNames=Moror_14444 {ECO:0000313|EMBL:ESK82196.1};
OS Moniliophthora roreri (strain MCA 2997) (Cocoa frosty pod rot fungus)
OS (Crinipellis roreri).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=1381753 {ECO:0000313|EMBL:ESK82196.1, ECO:0000313|Proteomes:UP000017559};
RN [1] {ECO:0000313|EMBL:ESK82196.1, ECO:0000313|Proteomes:UP000017559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 2997 {ECO:0000313|EMBL:ESK82196.1,
RC ECO:0000313|Proteomes:UP000017559};
RX PubMed=24571091; DOI=10.1186/1471-2164-15-164;
RA Meinhardt L.W., Costa G.G.L., Thomazella D.P.T., Teixeira P.J.P.L.,
RA Carazzolle M.F., Schuster S.C., Carlson J.E., Guiltinan M.J.,
RA Mieczkowski P., Farmer A., Ramaraj T., Crozier J., Davis R.E., Shao J.,
RA Melnick R.L., Pereira G.A.G., Bailey B.A.;
RT "Genome and secretome analysis of the hemibiotrophic fungal pathogen,
RT Moniliophthora roreri, which causes frosty pod rot disease of cacao:
RT mechanisms of the biotrophic and necrotrophic phases.";
RL BMC Genomics 15:164-164(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK82196.1}.
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DR EMBL; AWSO01002037; ESK82196.1; -; Genomic_DNA.
DR RefSeq; XP_007858498.1; XM_007860307.1.
DR AlphaFoldDB; V2WNV0; -.
DR KEGG; mrr:Moror_14444; -.
DR HOGENOM; CLU_000384_38_1_1; -.
DR OrthoDB; 1706856at2759; -.
DR Proteomes; UP000017559; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017559};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 1..83
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 455..615
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
SQ SEQUENCE 762 AA; 87924 MW; 74F31996A9B6925A CRC64;
MFFGLTNSPA TFQAFMNDIL KDFIDKGWCV VYMDDILIFS DEINIHRLRM RHVLERLREN
DLYLKLEKCE FEVTKTLFLG MVITPGHISM DEMKLAGIKD WEAPKTIKGV QSFLGFANFY
RKFIGKYAEL AQPLHELTKK DMKFEWTKTR DVAFNVLKAK FLQQLILQML DDEKLFVIEA
DASKWATGAV LKQQGPDGDL HPCGYISHAF TPTERNYEIY DRELLAITNA LKAWEHYLLG
GAHPVTVLSD HKNLTYFRTA QKLNRRQARL SLYLTQFDLQ LVHVPGTKMV QSDALSRQPD
LVDEEDNDNK DIVMLPDKLF VNVIDTELKT MLEEALPSDE FLQMTIESLI EKGTPPIKSS
LQDWQTEGNL LFYKDRIYMP NDPTLRKLIV KTIHEALPHG HPGQWNTVDQ VQRDYWWPGM
TKFIKSFVDG CAACQQMKVN THPMRTPIQP IGGHKDALPF QIISMDLITD LPKIADCDLI
LVVVDHVATK GVIFIPCHKK IDATDTAELL FQHVYKRFGL PDKIISDRDL RFAAKVFREM
GKLLGIKQML STTYHSQTDG ETERVNQEVE IFLRFFCTKE QTKWKDLLHF AEFAHNTQTH
SVTKNSPSYL TMGYHPRPLP TVFEKTTIPS MEKRVAELKK LREETSALLD IAARRVKERS
GKDLDRFKKG QKVWLEGKNL SLGYPSPKLS PKREGPFEIT EVLGPVTYRL KLPFQWRIHP
VFHAGLLSRY KETDVHGPNF MEPPPDIVEG QEEYEVKAII GH
//
