ID V2XN24_MONRO Unreviewed; 1109 AA.
AC V2XN24;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Vacuolar import and degradation protein 21 {ECO:0000256|ARBA:ARBA00029670};
GN ORFNames=Moror_8312 {ECO:0000313|EMBL:ESK94241.1};
OS Moniliophthora roreri (strain MCA 2997) (Cocoa frosty pod rot fungus)
OS (Crinipellis roreri).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=1381753 {ECO:0000313|EMBL:ESK94241.1, ECO:0000313|Proteomes:UP000017559};
RN [1] {ECO:0000313|EMBL:ESK94241.1, ECO:0000313|Proteomes:UP000017559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 2997 {ECO:0000313|EMBL:ESK94241.1,
RC ECO:0000313|Proteomes:UP000017559};
RX PubMed=24571091; DOI=10.1186/1471-2164-15-164;
RA Meinhardt L.W., Costa G.G.L., Thomazella D.P.T., Teixeira P.J.P.L.,
RA Carazzolle M.F., Schuster S.C., Carlson J.E., Guiltinan M.J.,
RA Mieczkowski P., Farmer A., Ramaraj T., Crozier J., Davis R.E., Shao J.,
RA Melnick R.L., Pereira G.A.G., Bailey B.A.;
RT "Genome and secretome analysis of the hemibiotrophic fungal pathogen,
RT Moniliophthora roreri, which causes frosty pod rot disease of cacao:
RT mechanisms of the biotrophic and necrotrophic phases.";
RL BMC Genomics 15:164-164(2014).
CC -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC is involved in transcriptional activation of selected genes principally
CC by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC also involved in DNA repair. {ECO:0000256|ARBA:ARBA00025178}.
CC -!- SIMILARITY: Belongs to the EAF1 family.
CC {ECO:0000256|ARBA:ARBA00008913}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK94241.1}.
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DR EMBL; AWSO01000148; ESK94241.1; -; Genomic_DNA.
DR RefSeq; XP_007846471.1; XM_007848280.1.
DR AlphaFoldDB; V2XN24; -.
DR STRING; 1381753.V2XN24; -.
DR KEGG; mrr:Moror_8312; -.
DR HOGENOM; CLU_006074_0_0_1; -.
DR OrthoDB; 1334563at2759; -.
DR Proteomes; UP000017559; Unassembled WGS sequence.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:UniProt.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd00167; SANT; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR014012; HSA_dom.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR PANTHER; PTHR46459:SF1; E1A-BINDING PROTEIN P400; 1.
DR PANTHER; PTHR46459; E1A-BINDING PROTEIN P400-RELATED; 1.
DR Pfam; PF07529; HSA; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR SMART; SM00573; HSA; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51204; HSA; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000017559}.
FT DOMAIN 204..286
FT /note="HSA"
FT /evidence="ECO:0000259|PROSITE:PS51204"
FT DOMAIN 612..667
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 612..663
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 86..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 784..815
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 940..1019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1072..1109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..510
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 784..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1109 AA; 123476 MW; C4CB01B26259313D CRC64;
MVVDDQDVPV VSSAADDPQT GEISQPPTQE SRPQEVTSIA PQLLEIHPRE SLVIHPTSSP
IYIPIPTLSY RTWNSVAFPA DSGFANQQQL TPPSPAHSRY NTESEYPLPP IKALPLEFNL
NKKGKHAKQK KKERERKDEW TPMGFNRWVM TIRTNPLYKR VSKATKCLTT HDWTIAMNEL
RVVRTSDRIE ALKAKGRWSF RQPKKQRGVG GTAKTHWDYL LEEMKWMRTD FREERKWKLA
LAYNLSTAVL EWHAAGSLEE RLKRGICVLW HPPRHDQDVE MSLDPTDEDN TGSQPSPEKS
MVDYGSDEDD EEEQEKEQNV LDAALDNTAL LEAFTSEENR DEQNIGMKDL ELKKEDIDDP
HALEDTIMTI DPEASQEASA TQKDEVDASA VPAGLKSVSD DPILGSKSNT HSSEPTNTHS
KSYKRSLYAP IRESIAYSDI DKLFVDLEDF HISSSDPDDS IHRTIHPPSD LSDIFPDLQP
YGILDVAPTN PPPEGKKKSD KKSDQDPNKR IEETAYTKIH HTSRFMSSKP TLVSALEPAK
HFKDGQWSSF DELSVTVEYE AAPVRVVSEE FANKLFDYKP TPLQIITPAV PNPPAQSSQP
PSVQRRSIEH LWTATDDSLL KSLIDKYPNN WDLIAECFNA IKQAVVTDIR TSRDCQERWR
DLYGQNQERQ RVLDTSGAEG TPPPTASTPN TMTTRGVKRV ASNSVSSAIG GPSIASEPKK
RRRHMFIQDT IRKSVKKRAE AAQKASVRKP AVLHETHNAY NKLPKLTPAE LGRMRLEAEL
RASQERQMSM NRQQQRQSVA QPAGQPVPAN GTPANGIARP AAAVAAAAAA AAPNPNAVPQ
IRSQVQVNIS QQQRAATPLI AGQSRLSPQH QQQQQQQQQQ QQQQQQQLLQ AQQRAQQLPS
QAQQQQIALS QQALAAALAH VQAQQAQNQV AAAAAAAAGG TATPQNNNVQ PAVNGNTTAM
SNSHLSPAYN IANSRDATSS PAHTSPPRTS ATPSNAVSSP RPPSAQAQAQ PAPQPQVQMQ
NGQIGAINIP RATNIQGHYY LPNMNLPNMQ SYGTTTQEQL HAMMILYQQQ HQQYQQQHQQ
QQQQPQQAQA QQQHQMQAQQ QQQSQQPQQ
//
