ID   V3Z571_LOTGI            Unreviewed;       564 AA.
AC   V3Z571;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   13-SEP-2023, entry version 46.
DE   RecName: Full=RING finger and SPRY domain-containing protein 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=LOTGIDRAFT_130506 {ECO:0000313|EMBL:ESO85848.1};
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO85848.1, ECO:0000313|Proteomes:UP000030746};
RN   [1] {ECO:0000313|EMBL:ESO85848.1, ECO:0000313|Proteomes:UP000030746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
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DR   EMBL; KB203251; ESO85848.1; -; Genomic_DNA.
DR   RefSeq; XP_009063577.1; XM_009065329.1.
DR   AlphaFoldDB; V3Z571; -.
DR   STRING; 225164.V3Z571; -.
DR   EnsemblMetazoa; LotgiT130506; LotgiP130506; LotgiG130506.
DR   GeneID; 20233084; -.
DR   KEGG; lgi:LOTGIDRAFT_130506; -.
DR   CTD; 20233084; -.
DR   HOGENOM; CLU_026400_0_0_1; -.
DR   OMA; KYSHDSV; -.
DR   OrthoDB; 170308at2759; -.
DR   Proteomes; UP000030746; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   CDD; cd16566; RING-HC_RSPRY1; 1.
DR   CDD; cd12883; SPRY_RING; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR045129; RNF123/RSPRY1-like.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR035774; SPRY_RSPRY1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR13363:SF6; RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR13363; RING FINGER AND SRY DOMAIN-CONTAINING; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   Pfam; PF13920; zf-C3HC4_3; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          270..453
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   DOMAIN          497..532
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          542..564
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        542..557
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   564 AA;  63631 MW;  823ECB328B7AC5B4 CRC64;
     MGCCLTTCNK KEDDHYQPNT ESSPLSSRDG RRRSSYGHQS PQRSTNGYSQ RRRLGSSHSR
     DNPQRSIDSL VLETLSLIRT LVDNDQEPPQ AMLALHKIAE KDSGWLEVVK SLIRGIPLTD
     PLGPAVITLL LDEFPLPTKE ALMELRSNLH LSQEGISNMY KQPCQQRNIG VILGCLAEKL
     AGPNSVSLLS SDVLQYLISN LSVNNHPVVI LHSMVALEKF AQTSENKVTI NQSLGEMKTN
     PLVSLEAWSS SDEYAKREVA FCARWCLDNL FMIQGRPFTY EQLVHDNINV MLNSNDVSEY
     LKISANGLEA RCDASSFESV RCTFQVDSGI WYYEVTIITA GVMQIGWATK NSKFLNHEGF
     GIGDDEFSMA YDGCRQLIWY NAHSEPHTHR CWQPGDTLGL LLDLENHQLV FYLNGDPLPP
     YCQVFSCTRT GFFAAASFMS FQQCEFNFGA KPFKYPPKFK FEKFNDKGTL TEEEKVILPR
     HKKLDLLKQV LVKEDSCTLC FDKQANMELH PCGHNGFCDV CSLQLETCPI CRKPIIERRE
     LSIRSTNSST SSPSPEPHTF DRPS
//