ID V3ZEL4_LOTGI Unreviewed; 357 AA.
AC V3ZEL4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 22-FEB-2023, entry version 42.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_134475 {ECO:0000313|EMBL:ESO82527.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO82527.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO82527.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB203855; ESO82527.1; -; Genomic_DNA.
DR RefSeq; XP_009066720.1; XM_009068472.1.
DR AlphaFoldDB; V3ZEL4; -.
DR STRING; 225164.V3ZEL4; -.
DR EnsemblMetazoa; LotgiT134475; LotgiP134475; LotgiG134475.
DR GeneID; 20233561; -.
DR KEGG; lgi:LOTGIDRAFT_134475; -.
DR CTD; 20233561; -.
DR HOGENOM; CLU_021968_0_0_1; -.
DR OMA; LRDPRMC; -.
DR OrthoDB; 2881273at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd13244; PH_PLEKHG5_G6; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR040181; PKHG5/7.
DR PANTHER; PTHR13217:SF11; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5; 1.
DR PANTHER; PTHR13217; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT DOMAIN 1..193
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESO82527.1"
SQ SEQUENCE 357 AA; 42232 MW; 003032A330842F0C CRC64;
QQEAIWELIE TEKSFIKNLN VITDVFKNCL LNIQNNQLLS EIETEQLFSN IDALEEVNCQ
FWEQHILPVL NDSRSSRQPL NPSLFKQGFT TQFHKLFHPY VKWCIDQKNC VDYQRTKYSE
NELFKTFVVW AEAQPQCKRL KLTDLLAKPM QRLTKYSLLV NAILKKTEDP HQRQDLEEMI
EHIDRFVTHV NTQLRNQQEQ ERYESIIAKI EPYDAIEAPN EECVKILQEY NTNFDLRAPM
PGINQVSRKL LMQSALKLKD AQARMEVDCF LFTDLFLICK SNKRMDKYKV LKPPMRLDRI
LVHDLKDKGS FLLIYLNEYH VPSTAYTFHA NESAVKCWLE YIKKAQVSIC LLSWSRS
//
