ID V4ATI0_LOTGI Unreviewed; 1009 AA.
AC V4ATI0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=LOTGIDRAFT_143556 {ECO:0000313|EMBL:ESO97046.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO97046.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO97046.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KB201360; ESO97046.1; -; Genomic_DNA.
DR RefSeq; XP_009052270.1; XM_009054022.1.
DR AlphaFoldDB; V4ATI0; -.
DR STRING; 225164.V4ATI0; -.
DR EnsemblMetazoa; LotgiT143556; LotgiP143556; LotgiG143556.
DR GeneID; 20234710; -.
DR KEGG; lgi:LOTGIDRAFT_143556; -.
DR CTD; 20234710; -.
DR HOGENOM; CLU_000192_7_7_1; -.
DR OMA; VVFFKCL; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF713; UNCONVENTIONAL MYOSIN ID; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT DOMAIN 10..699
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 816..1008
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT REGION 577..599
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 103..110
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1009 AA; 114943 MW; 41239D1F276BE70D CRC64;
MAGIHEGPEF GIGDFVLLRD VTLDGFMENL KLRFQKGKIY TYIGEVVVSV NPYRPIDIYN
TSYVEQYRGR EIYERPPHIF ALADSAYKNM KRNSKDTCIV ISGESGAGKT EASKIIMRYI
AAVTNISGQK EVERVKDILI KSNVILETFG NAKTNRNDNS SRFGKYMDIN FDFKGDPIGG
HINNYLLEKS RVVYQQEGER TFHSFYQLLS GGSEKQLSDL KLSRDCSKYY FISQGGSSQV
PTINDKREFK AVNDAMKGAG FSAEHISSLW KIVAAVIHLG DIKFEADPDQ HEQVLISNQN
NLNDIARLFS VDVDALQKAL CFRTIAAGGQ VVEKGLKQTE AHYARDAFAK ATYDRMFSWI
VGRINELIDP KISGLKYVGK NTVIGVLDIY GFEIFDNNSF EQFCINYCNE KLQQLFIELV
LKQEQEEYMK EGIEWQHVDY FNNKVICDLV ELQHKGILAI LDEACLNVGK VTDVMFLQAM
ATKLNKHDRF TCRSLNAADK TLQHDRDFRI RHYAGDVSYS VIGFIDKNKD TLFQDFKRLL
YNSKDELIKS MWPEGKQSVT ETTRRPVTAG TNFKNSIIAL VENLASKEPH YVRCIKPNEL
KSPSVFDDER VGHQVRYLGL IENVRVRRAG FAFRMHYDRF LRRYKCICKK TWPTFHGTDY
DGTICIIKEK GFSDDVKYGR SKIFIRSPQT LFALEEARDS VIPSIVAYLQ KNWRGGLGRM
KARKVRAIYK IMARYRKYKM RSYILKCVSI FKNVRTMPGY GKNITWPRPP NVLEGLVALL
LKVHRRWRAN MILRNVPMSE RPVLRLKVTA GDVLKGKRSD WGVKRKWEGN YLASTKDNSA
TADFVSQAAT LKGQDGYSKI LFSSFVKKVN KHNKMADRGI IITNKSIYKL DSKKRFKPMT
KGTPISEITG LSITPESDQL VVIHLSGGND LVICLISQSG EERVGELVGI LCSHWHKTMK
KDLKVNISKQ FNVMLGGKSR TVTVKTTVAN GGPSFKKDGQ GLALFWPVQ
//
