ID V4B2J1_LOTGI Unreviewed; 247 AA.
AC V4B2J1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=c-SKI SMAD4-binding domain-containing protein {ECO:0000259|SMART:SM01046};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_112155 {ECO:0000313|EMBL:ESP00617.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP00617.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP00617.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the SKI family. {ECO:0000256|ARBA:ARBA00009513}.
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DR EMBL; KB200701; ESP00617.1; -; Genomic_DNA.
DR RefSeq; XP_009048736.1; XM_009050488.1.
DR AlphaFoldDB; V4B2J1; -.
DR EnsemblMetazoa; LotgiT112155; LotgiP112155; LotgiG112155.
DR GeneID; 20230823; -.
DR KEGG; lgi:LOTGIDRAFT_112155; -.
DR CTD; 20230823; -.
DR HOGENOM; CLU_030459_2_0_1; -.
DR OMA; XIRTRSI; -.
DR OrthoDB; 2898797at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0046332; F:SMAD binding; IEA:InterPro.
DR CDD; cd21080; DHD_Skor; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR Gene3D; 3.10.260.20; Ski; 1.
DR InterPro; IPR014890; c-SKI_SMAD4-bd_dom.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR003380; SKI/SNO/DAC.
DR InterPro; IPR037000; Ski_DNA-bd_sf.
DR InterPro; IPR023216; Tscrpt_reg_SKI_SnoN.
DR PANTHER; PTHR10005:SF26; CORL; 1.
DR PANTHER; PTHR10005; SKI ONCOGENE-RELATED; 1.
DR Pfam; PF08782; c-SKI_SMAD_bind; 1.
DR Pfam; PF02437; Ski_Sno; 1.
DR SMART; SM01046; c-SKI_SMAD_bind; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR SUPFAM; SSF63763; SAND domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT DOMAIN 145..237
FT /note="c-SKI SMAD4-binding"
FT /evidence="ECO:0000259|SMART:SM01046"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 247
FT /evidence="ECO:0000313|EMBL:ESP00617.1"
SQ SEQUENCE 247 AA; 28155 MW; 6ABDEFF61C2DF268 CRC64;
MNTPVVDEYP KSPSSSINST SPLNIPTLER VQPTSNVRQN TVTTVNLHNV SIVCLRIDGK
ERLCLAQISN TLLKEYSYNE IHNRRVALGI TCVQCTPVQL EILRRAGAMP VSSRRCGMIT
KREAERLVKS FLEDSTPPKL PENFSFEVYH ECGWGCTGFF EPSRYNSSRA KCIKCSLCNM
HLSPNKFIFH NHRTPTSKYH HPDAANFNSW RRHLKLTSEA EKSDFSYAWE DVKAMFNGGS
RKRILNS
//
