ID V4BBF5_LOTGI Unreviewed; 437 AA.
AC V4BBF5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
GN ORFNames=LOTGIDRAFT_237684 {ECO:0000313|EMBL:ESP03372.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP03372.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP03372.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB200027; ESP03372.1; -; Genomic_DNA.
DR RefSeq; XP_009045905.1; XM_009047657.1.
DR AlphaFoldDB; V4BBF5; -.
DR STRING; 225164.V4BBF5; -.
DR EnsemblMetazoa; LotgiT237684; LotgiP237684; LotgiG237684.
DR GeneID; 20250526; -.
DR KEGG; lgi:LOTGIDRAFT_237684; -.
DR CTD; 20250526; -.
DR HOGENOM; CLU_035647_1_0_1; -.
DR OMA; YINCAAN; -.
DR OrthoDB; 2962435at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24243; G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24243:SF208; PYROKININ 2 RECEPTOR 1-RELATED; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..413
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 289..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 49147 MW; F342208B61515B19 CRC64;
MEPMPNIVTG KMLNSTARNA TKIVLPPNYV QLLNEKMVWV MIVPIIYVAV MMVIGLIGNI
LVVYVYGFRW QRTPIKCFIT TLAVFDLINC TITMPTEIAI LVNFFSFDAH IFCKISRFST
FWMNNSSVVL LFAIAIDRFI KICMPNKKSF DYHKAKVTCT VSTIIGIVVS WPALVVYGNK
TFPLPPNGQF MATQCSVADG LEKTTFPIGF YVYLWVAFLA IALVMIILYA LIGAKIWMQK
SKGDKRKNSL KASLRSTGSN SQANDKEISV ISVKKLADVE KTNSMELSDD AFDDNATSSS
DEQKKVQVQT PVKMPEKKEP RTSTSKSPLK SLSTFSRSIS ISKSGLQAGK ATMMLFVITM
VYILSFLPFL IVSILLTTRG PMWYIAMSPN SQMLVQLFMR SYLISNTGNA IVYGFGNQKF
RGECRKAFKR MCRRNIR
//
