ID V4BD05_LOTGI Unreviewed; 376 AA.
AC V4BD05;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Integrin beta subunit tail domain-containing protein {ECO:0000259|SMART:SM01242};
GN ORFNames=LOTGIDRAFT_228160 {ECO:0000313|EMBL:ESP05686.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP05686.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP05686.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the integrin beta chain family.
CC {ECO:0000256|ARBA:ARBA00007449}.
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DR EMBL; KB199650; ESP05686.1; -; Genomic_DNA.
DR RefSeq; XP_009044231.1; XM_009045983.1.
DR AlphaFoldDB; V4BD05; -.
DR STRING; 225164.V4BD05; -.
DR EnsemblMetazoa; LotgiT228160; LotgiP228160; LotgiG228160.
DR GeneID; 20247562; -.
DR KEGG; lgi:LOTGIDRAFT_228160; -.
DR CTD; 20247562; -.
DR HOGENOM; CLU_736275_0_0_1; -.
DR OMA; CECAATE; -.
DR OrthoDB; 3037350at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 4.10.1240.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR InterPro; IPR040622; I-EGF_1.
DR InterPro; IPR015812; Integrin_bsu.
DR InterPro; IPR012896; Integrin_bsu_tail.
DR InterPro; IPR036349; Integrin_bsu_tail_dom_sf.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR10082; INTEGRIN BETA SUBUNIT; 1.
DR PANTHER; PTHR10082:SF60; INTEGRIN BETA-PS; 1.
DR Pfam; PF18372; I-EGF_1; 2.
DR Pfam; PF07965; Integrin_B_tail; 1.
DR SMART; SM01242; Integrin_B_tail; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF69687; Integrin beta tail domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 1.
DR PROSITE; PS00243; INTEGRIN_BETA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}.
FT DOMAIN 295..375
FT /note="Integrin beta subunit tail"
FT /evidence="ECO:0000259|SMART:SM01242"
SQ SEQUENCE 376 AA; 42195 MW; C69B3A2C02CD13A3 CRC64;
MDMDYRLLRN EPLSTMHSKR IAPQQISLNI KKASGKETEV QFEATAAKRW LATKISFPRR
KYSITMTSTC RFRWRDSGRG RCSRTRRGQT LTFTLKIRVL DCNDGNGRIT VSIPGYTQDK
LNIEIRSSCP CSCEQNKERN SAVCRGNGHL SCGTCECSDG YFGQQCECMG YERDTCRARP
DSTVCSGRGN CVCGMCECQA GFEGQHCECN NENCNWFNNS ICGGSDHGIC NCGECTCKPE
YTGTACELPM STDGCIAPNG IICNGHGNCI GNTCQCRGTY RGRTCDQCPT CIGQCSILWP
CIQCTIFQTG ELTREDCYYQ CRQYGIMPVD SLERRESSRL CMFRDDDNCS VSFMYMFDED
GELVVEASRQ KNCARQ
//
