ID V4CQU1_LOTGI Unreviewed; 457 AA.
AC V4CQU1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
GN ORFNames=LOTGIDRAFT_109284 {ECO:0000313|EMBL:ESP04830.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESP04830.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESP04830.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KB199651; ESP04830.1; -; Genomic_DNA.
DR RefSeq; XP_009044339.1; XM_009046091.1.
DR AlphaFoldDB; V4CQU1; -.
DR STRING; 225164.V4CQU1; -.
DR EnsemblMetazoa; LotgiT109284; LotgiP109284; LotgiG109284.
DR GeneID; 20230451; -.
DR KEGG; lgi:LOTGIDRAFT_109284; -.
DR CTD; 20230451; -.
DR HOGENOM; CLU_012560_7_0_1; -.
DR OMA; EMLEFQS; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 2.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR PANTHER; PTHR45721:SF12; INTERMEDIATE FILAMENT PROTEIN IFA-1; 1.
DR PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR Pfam; PF00038; Filament; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746}.
FT DOMAIN 77..429
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 67..221
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 348..428
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 25..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 51874 MW; E4C82083FFC82BF8 CRC64;
MSTKGQQKQE FASSGRGGSG FIHGRTTLIT RSGKNPTPSG YSMRSSFGGG LLNMAPGTYQ
NMSHEGVVNV KGKREHEKKE MQSLNERLAS YIDKVRFLEA RNAQLEQELD VYRNQKQADF
KPIRDQYETE LNQARRVIDE LAGEKANYDA KMAGLQDLVD SLKDTNETLE NHNNELRQKI
DNQSTQIGSY EGELGTLRLR IESLEDENKH LRELLKKRSD ENMALRTDLD NETAAHIEAD
CRATTLEEEV DFLKALLDKM PQESQKPVLI KGQNLEDFWK NSMSKAIRDI QNEYENKLDI
MRQDMEMRMQ SQVRQLQSGA VRDNMETTHA REESKKLKSQ LGDTASRITN LEGMVAALES
ERNDLRRKLA LSEDELATEK AAHQDDRARL TAEMESVLAE LQQIMDAKLS LELEIACYRQ
LLEGEENRLG MKSIVEQAIG TRTKGAGNLS DIVQQTS
//
