ID V4JT61_EUTSA Unreviewed; 452 AA.
AC V4JT61;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Glycerate dehydrogenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10018534mg {ECO:0000313|EMBL:ESQ28480.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ28480.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ28480.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; KI517953; ESQ28480.1; -; Genomic_DNA.
DR RefSeq; XP_006391194.1; XM_006391132.1.
DR AlphaFoldDB; V4JT61; -.
DR STRING; 72664.V4JT61; -.
DR EnsemblPlants; ESQ28480; ESQ28480; EUTSA_v10018534mg.
DR GeneID; 18007823; -.
DR Gramene; ESQ28480; ESQ28480; EUTSA_v10018534mg.
DR KEGG; eus:EUTSA_v10018534mg; -.
DR eggNOG; KOG0069; Eukaryota.
DR OMA; RMMVEGH; -.
DR OrthoDB; 6392at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR10996:SF257; GLYCERATE DEHYDROGENASE HPR, PEROXISOMAL; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689}.
FT DOMAIN 96..413
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 196..388
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 452 AA; 50249 MW; ADFA2C6A7A2119F0 CRC64;
MNHTQKQNKK LQIIYMQNRP LDFLFDFKPQ KFLLSELKNW TFFKSQDTLF PNSRHSLLEA
FFFCSPMAKP VAIEVYNPNG KYRVVSTKPM PGTRWINLLI DQGCRVEICH LKKTILSVED
IIDLIGNKCD GVIGQLTEDW GETLFSALSK AGGKAFSNMA VGYNNVDVEA ANKYGIAVGN
TPGVLTETTA ELAASLSLAA ARRIVEADGF MRAGLYEGWL PHLFVGNLLK GQTVGVIGAG
RIGSAYARMM VEGFKMNLIY YDLYQSTRLE KFVTAYGQFL KANGEQPVTW KRASSMEEVL
READLISLHP VLDKTTYHLV NKERLAIMKK EAILVNCSRG PVIDEAALVD HLRENPMFRV
GLDVFEEEPF MKPGLADMKN AIVVPHIASA SKWTREGMAT LAALNVLGRI KGYPIWSDPN
RVDPFLNENA SPPNASPSIV NSKALGLPVS KL
//
