ID V4K8A1_EUTSA Unreviewed; 273 AA.
AC V4K8A1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Calcyclin-binding protein {ECO:0000256|ARBA:ARBA00015702};
GN ORFNames=EUTSA_v10008455mg {ECO:0000313|EMBL:ESQ33870.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ33870.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ33870.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- FUNCTION: May be involved in calcium-dependent ubiquitination and
CC subsequent proteasomal degradation of target proteins. Probably serves
CC as a molecular bridge in ubiquitin E3 complexes. Participates in the
CC ubiquitin-mediated degradation of beta-catenin (CTNNB1).
CC {ECO:0000256|ARBA:ARBA00025145}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KI517683; ESQ33870.1; -; Genomic_DNA.
DR RefSeq; XP_006415517.1; XM_006415454.1.
DR AlphaFoldDB; V4K8A1; -.
DR STRING; 72664.V4K8A1; -.
DR EnsemblPlants; ESQ33870; ESQ33870; EUTSA_v10008455mg.
DR Gramene; ESQ33870; ESQ33870; EUTSA_v10008455mg.
DR KEGG; eus:EUTSA_v10008455mg; -.
DR eggNOG; KOG3260; Eukaryota.
DR OMA; NWKYLTK; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0044548; F:S100 protein binding; IEA:InterPro.
DR GO; GO:0015631; F:tubulin binding; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006950; P:response to stress; IEA:UniProt.
DR CDD; cd06468; p23_CacyBP; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR037201; CacyBP_N.
DR InterPro; IPR037893; CS_CacyBP.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR007699; SGS_dom.
DR InterPro; IPR015120; Siah-Interact_N.
DR PANTHER; PTHR47686:SF1; CALCYCLIN-BINDING PROTEIN; 1.
DR PANTHER; PTHR47686; SGS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF04969; CS; 1.
DR Pfam; PF09032; Siah-Interact_N; 1.
DR SUPFAM; SSF140106; Calcyclin-binding protein-like; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS51048; SGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 125..215
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT DOMAIN 200..273
FT /note="SGS"
FT /evidence="ECO:0000259|PROSITE:PS51048"
SQ SEQUENCE 273 AA; 30813 MW; B6A15BCE9344CB7C CRC64;
MSIKLHVDVG TWIPLAHILY QFSYPLSQLY IMEESNLSTF CLLEKDCSKI TSMAEEAVLD
LEELRQLQNI AKRPRVLNLI NSEICNLEKL RQSASGSSAK PEVEVAAPAS VSSSVKPVSP
AVNYVTLGTF SWDQDNEKVK MYISLEGVDQ DKVQAEFKPM SLDIKIHDVQ GKNYRCAIPK
LHKEIVPEKC KVLVKPKRIV ITMFKSSRGN WVDIHHKEDK IKPSFEKEKD PMAGIMDLMK
NMYEGGDEEM KKTIAKAWTD ARSGKTADPL KGL
//
