ID V4KKP9_EUTSA Unreviewed; 490 AA.
AC V4KKP9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Abietadienol/abietadienal oxidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10018455mg {ECO:0000313|EMBL:ESQ27853.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ27853.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ27853.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|PIRSR:PIRSR602403-1};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KI517953; ESQ27853.1; -; Genomic_DNA.
DR RefSeq; XP_006390567.1; XM_006390505.1.
DR AlphaFoldDB; V4KKP9; -.
DR STRING; 72664.V4KKP9; -.
DR EnsemblPlants; ESQ27853; ESQ27853; EUTSA_v10018455mg.
DR GeneID; 18009284; -.
DR Gramene; ESQ27853; ESQ27853; EUTSA_v10018455mg.
DR KEGG; eus:EUTSA_v10018455mg; -.
DR eggNOG; KOG0157; Eukaryota.
DR OMA; TMDFTQC; -.
DR OrthoDB; 758626at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11043; CYP90-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002403; Cyt_P450_E_grp-IV.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24286; CYTOCHROME P450 26; 1.
DR PANTHER; PTHR24286:SF232; CYTOCHROME P450 SUPERFAMILY PROTEIN; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00465; EP450IV.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR602403-1};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR602403-1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR602403-1};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT BINDING 433
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR602403-1"
SQ SEQUENCE 490 AA; 56003 MW; 928681BA94B277AE CRC64;
MTEFTGESYW LLSAAASTTF LAFIIIFFLA GIARRKRREP HKLPPGSRGW PLIGDTFAWL
SAVSGSHPSR FVEKQIKRYG RIFSCSLFGK WAVVSADPEF NRFIMQNEGK LFQSSYPKSF
RDLVGKDGVI TVHGNQQRRL HSIASSMMRQ DQLKTHFLED IPAVMLQTLS NFKDGEVVLL
QDICRKVAIH LVVNQLLGVS SESEVDEMSQ LFSDFVDGCL SVPINLPGFT YHKAMKARKE
IISKINKTIE KLLQNKAASE AADTSGNGVL GRLLENESLP NESMADFIIN LMFAGNETTA
KTMLFAVYFL THCPKAMTQI MEEHERLAGG MLTWQDYKTM DFTQCVIDET LRLGGIAIWL
MREAKEDVSY QDYVIPKGCF VVPFLSAVHL DESYYKESLS FDPWRWLDPE TQQKRNWRTS
SFYCPFGGGT RFCPGAELAR LQIALFLHYF ITTYRWTQLK EDRISFFPSA RLVNGFKIQL
NRRDNDPQRQ
//
