ID V4L0U7_EUTSA Unreviewed; 1013 AA.
AC V4L0U7;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Histone-lysine N-methyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10005766mg {ECO:0000313|EMBL:ESQ43900.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ43900.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ43900.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI517455; ESQ43900.1; -; Genomic_DNA.
DR RefSeq; XP_006402447.1; XM_006402384.1.
DR AlphaFoldDB; V4L0U7; -.
DR STRING; 72664.V4L0U7; -.
DR EnsemblPlants; ESQ43900; ESQ43900; EUTSA_v10005766mg.
DR GeneID; 18020324; -.
DR Gramene; ESQ43900; ESQ43900; EUTSA_v10005766mg.
DR KEGG; eus:EUTSA_v10005766mg; -.
DR eggNOG; KOG1080; Eukaryota.
DR OMA; SHGSCIT; -.
DR OrthoDB; 304343at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:EnsemblPlants.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IEA:EnsemblPlants.
DR CDD; cd15663; ePHD_ATX3_4_5_like; 1.
DR CDD; cd15495; PHD_ATX3_4_5_like; 1.
DR CDD; cd15517; PHD_TCF19_like; 1.
DR CDD; cd20143; PWWP_AtATX3-like; 1.
DR CDD; cd10518; SET_SETD1-like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR041955; ATX3/4/5_ePHD.
DR InterPro; IPR042011; ATX3/4/5_PHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR025780; Hist-Lys_N-MeTrfase_ATX.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF92; HISTONE-LYSINE N-METHYLTRANSFERASE ATX3; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00293; PWWP; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS51566; SAM_MT43_TRX_MLL; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 214..283
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 390..446
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 574..625
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 628..743
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 870..988
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 997..1013
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 37..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1013 AA; 114194 MW; 3DDDAEE68A76A967 CRC64;
MILKRTLTFE NQNLKQCKID SEIDYGSKKG EIMVYKKRQR ASVDQPCREP EDLTSSGGSL
TSKESHLGSD QSKSSRGRVR VVPSRFNDSV VDAWNTRRRK VELKEPSHDD DIHVVKKVKG
GGHDMSRSSK FNLSKGRKLF PRKDNGDGSE LDFDDWGNEK DANISMLSSS DDANSFSVRG
KEQSFSGRNL AESGTLKNPT AMRKGVYKPE DFAVGDLVWA KSGKRFPAWP AKVIDPISQA
PDAVLKHYVP GSLCVMFFGH SKNGTQRDYG WVRQGMMFPF TEFMDKFQDQ TNLYNNNPNE
FKKALEEAIL ADNGVEGNCG AAEISCPDSS ATESDQEHGP AYRIQESFHV DIRTCDGCGT
VMPSKSLKRT KGSQPEEFLC KRCSKLRKSN QYCGICKILW DSSDGGDWVC CDGCDIWVHA
GCDNISNKRF KELEHNNYHC PNCRAQHERA STVLDEQNSL FKSTEKATET ELPDEITVVC
NGMEGTYITK FHAIECKCGS CGARKQTPSE WERHTGCRAK KWKYSVKVKG TMLTLEKWIA
GFSAPTLETQ MLDKQKMLSL LEEKYEPVSA KWTTERCAVC RWVEDWEENK MIICNRCQVA
VHQECYGVSK AQDLTSWVCR ACETPDIERE CCLCPVKGGA LKPSDVEGLW VHVTCAWFRP
EVGFLNHENM EPAVGLFKIP ANSFLRVCRI CKQTHGSCVQ CCKCATHFHA MCASRAGYSM
ELHCLEKNGV QRTRKSIYCA FHRKPDPNSN VVVHTPSGVF GSRNLLQNQN GRIKGSRLVL
TKKIKLPGSD IQPQAEQSHE FDSLSAARCR IYSRSNTKKI DLEAIYHRLK GPSHHSLGAI
ENLNSLKKAD TSDFTSFKER LKHLQRTENL RVCFGKSGIH GWGLFAKTSI QEGEMIIEYR
GVKVRRSVAD LREANYRSQG KDCYLFKISE EIVIDATDSG NIARLINHSC MPNCYARIVS
MGDGEENRIV LIAKTNVSAG EELTYDYLFE VDESEEIKVP CLCRAPNCRK FMN
//
