ID V4L1D6_EUTSA Unreviewed; 1034 AA.
AC V4L1D6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=EUTSA_v10006650mg {ECO:0000313|EMBL:ESQ33538.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ33538.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ33538.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KI517683; ESQ33538.1; -; Genomic_DNA.
DR RefSeq; XP_006415185.1; XM_006415122.1.
DR AlphaFoldDB; V4L1D6; -.
DR EnsemblPlants; ESQ33538; ESQ33538; EUTSA_v10006650mg.
DR Gramene; ESQ33538; ESQ33538; EUTSA_v10006650mg.
DR KEGG; eus:EUTSA_v10006650mg; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689}.
FT DOMAIN 404..567
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 590..765
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 103..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 225..252
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 107..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1034 AA; 117564 MW; A1318D5FB9FA1B18 CRC64;
MASNDLKTWV SDKLMVLLGY SQTAVVNYLI AMAKKSKSPA ELVGELVDYG FSSSGDTRSF
AEEIFARVPR KAAGVNLYQQ REEEAAMLVR KQKTYALLDA DDDEDEVVVE KKPSASESRK
SDKGKKRFRK KSGQSDDSED EVSVREDNRH VKRKVSEDED DGSESEEEML RDQKEREELE
QHLRDRDTAR TRKLTEQKLS KKEQEEAVRR ANALEKDDLH SLRKVSRQEY LKKREQKKLE
ELRDEIEDEQ YLFGGEKLTE TELREFRYKK ELYDLVKKRT QDEDNVEEGG VDQEKRFAVA
VQRYRDLDST EKMNPFAEQE AWEDHQIGKA TLKFGAKNKQ ASDDYQFVFE DQINFIKESV
MAGENYEHDM DAKESQDAAE RTALEELQEV RKSLPIYAYR EQLLQAVEEH QVLVIVGDTG
SGKTTQIPQY LHEAGYTKRG KVGCTQPRRV AAMSVAARVA QEMGVKLGHE VGYSIRFEDC
TSDKTVLKYM TDGMLLRELL GEPDLASYSV VIVDEAHERT LSTDILFGLV KDIARFRPDL
KLLISSATMD AEKFSDYFDT APIFSFPGRR YPVEINFTSA PEADYMDAAI VTVLTIHVRE
PLGDILVFFT GQEEIETAEE ILKHRIRGLG TKIRELIICP IYANLPSELQ AKIFEPTPEG
ARKVVLATNI AETSLTIDGI KYVVDPGFSK MKSYNPRTGM ESLLITPISK ASATQRAGRA
GRTSAGKCYR LYTAFNYNND LEENTVPEVQ RTNLASVVLA LKSLGIHDLI NFDFMDPPPA
EALVKALELL FALGALNKLG ELTKAGRRMA EFPLDPMLSK MIVVSDKYKC SDEIISIAAM
LSVGGSIFYR PKDKQVHADN ARMNFHTGNV GDHIALLKVY SSWKETNYST QWCYENYIQV
RSMKRARDIR DQLEGLLERV EIEISSNLND LDSVRKSIVA GFFPHTAKLQ KNGSYRTVKH
PQTVHIHPNS GLSQVLPRWV VYHELVLTSK EYMRQVTELK PEWLIELAPH YYQLKDVEDG
ASKKMPKGAG KAAM
//
