ID V4LA61_EUTSA Unreviewed; 604 AA.
AC V4LA61;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=4Fe-4S Mo/W bis-MGD-type domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EUTSA_v100276401mg {ECO:0000313|EMBL:ESQ47320.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ47320.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ47320.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 75 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00005404}.
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DR EMBL; KI517416; ESQ47320.1; -; Genomic_DNA.
DR RefSeq; XP_006405867.1; XM_006405804.1.
DR AlphaFoldDB; V4LA61; -.
DR STRING; 72664.V4LA61; -.
DR EnsemblPlants; ESQ47320; ESQ47320; EUTSA_v100276401mg.
DR GeneID; 18022801; -.
DR Gramene; ESQ47320; ESQ47320; EUTSA_v100276401mg.
DR KEGG; eus:EUTSA_v100276401m; -.
DR eggNOG; KOG2282; Eukaryota.
DR OMA; QDQAMAY; -.
DR OrthoDB; 19999at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR CDD; cd02773; MopB_Res-Cmplx1_Nad11; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.740; -; 2.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS.
DR InterPro; IPR010228; NADH_UbQ_OxRdtase_Gsu.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR InterPro; IPR015405; NDUFS1-like_C.
DR NCBIfam; TIGR01973; NuoG; 1.
DR PANTHER; PTHR43105:SF13; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF10588; NADH-G_4Fe-4S_3; 1.
DR Pfam; PF09326; NADH_dhqG_C; 1.
DR SMART; SM00929; NADH-G_4Fe-4S_3; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00642; COMPLEX1_75K_2; 1.
DR PROSITE; PS00643; COMPLEX1_75K_3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 9..48
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 146..202
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESQ47320.1"
SQ SEQUENCE 604 AA; 66038 MW; BF90E9C3EE2D67BA CRC64;
MKIKTDTPIA KKAREGVMEF LLMNHPLDCP ICDQGGECDL QDQSMAFGSD RGRFTEMKRS
VVDKNLGPLV KTVMTRCIQC TRCVRFASEV AGVEDLGMLG RGSGEEIGTY VEKLMTSELS
GNVIDICPVG ALTSKPFAFK ARNWELKGTE TIDVSDAVGS NIRVDSRGPE VMRIIPRLNE
DINEEWISDK TRFSYDGLKR QRLSDPMIRD SDGRFKAVSW RDALAVVGDI VHQVKSDEIV
GIAGQLSDAE SMMVLKDFVN RMGSDNVWCE GTAVGVDADL RYSYLMNTSI SGLENADLFL
LVGTQPRVEA AMVNARICKT VRASNAKVAY IGPPTDFNYD CKHLGTGPDT LKEIAEGSHP
FCSALKNAKK PAIIVGAGLF NRTDKDAILS AVESIAQANN VVRPDWNGLN YLLLYAAQAA
ALDIGLVQQS AKALDSAKFV YLMGADDVDV DKIPKDAFVV YQGHHGDKAV YRANVILPAS
AFTEKEGTYE NTEGFTQQTV PAVPTVGDAR DDWKIVRALA EVSGVKLPYN SIDGVRSRIK
SVAPNLVHTD EREPAAFGPS LKPECKETMS KTPFQTVVEN FYMTNSITRA SKIMAQCSAV
LLKK
//
