ID V4LDN1_9GAMM Unreviewed; 122 AA.
AC V4LDN1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Ribosomal RNA small subunit methyltransferase D {ECO:0000256|ARBA:ARBA00013682};
DE EC=2.1.1.171 {ECO:0000256|ARBA:ARBA00012141};
DE AltName: Full=16S rRNA m2G966 methyltransferase {ECO:0000256|ARBA:ARBA00031268};
DE AltName: Full=rRNA (guanine-N(2)-)-methyltransferase {ECO:0000256|ARBA:ARBA00033371};
GN ORFNames=N838_09985 {ECO:0000313|EMBL:ESQ14998.1};
OS Thiohalocapsa sp. PB-PSB1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Thiohalocapsa.
OX NCBI_TaxID=1385625 {ECO:0000313|EMBL:ESQ14998.1, ECO:0000313|Proteomes:UP000017935};
RN [1] {ECO:0000313|EMBL:ESQ14998.1, ECO:0000313|Proteomes:UP000017935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilbanks E.G., Jaekel U., Salman V., Humphrey P.T., Eisen J.A.,
RA Facciotti M.T., Buckley D.H., Zinder S.H., Druschel G.K., Fike D.A.,
RA Orphan V.J.;
RT "A sulfurous symbiosis: microscale sulfur cycling in the pink berry
RT consortia of the Sippewissett salt marsh.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Specifically methylates the guanine in position 966 of 16S
CC rRNA in the assembled 30S particle. {ECO:0000256|ARBA:ARBA00002649}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:23548, Rhea:RHEA-COMP:10211, Rhea:RHEA-COMP:10212,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.171;
CC Evidence={ECO:0000256|ARBA:ARBA00000252};
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmD family.
CC {ECO:0000256|ARBA:ARBA00005269}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESQ14998.1}.
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DR EMBL; AVFR01000500; ESQ14998.1; -; Genomic_DNA.
DR AlphaFoldDB; V4LDN1; -.
DR Proteomes; UP000017935; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0031167; P:rRNA methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR004398; RNA_MeTrfase_RsmD.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43542; METHYLTRANSFERASE; 1.
DR PANTHER; PTHR43542:SF1; METHYLTRANSFERASE; 1.
DR Pfam; PF03602; Cons_hypoth95; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000017935}.
SQ SEQUENCE 122 AA; 13137 MW; ED30EAFB0CFFCA9C CRC64;
MIESAGAAVM QLRSNVQLIK AEKVRVIKAD ALRWLSTQEP KPMDIIFLDP PFASGLLAPA
IDKLESKGWV HPGSLLYLET QSSGSPPSLP VAWSLLRHKR AGQVCYGLAR VGGVELALIG
HA
//
