ID V4LN53_EUTSA Unreviewed; 1143 AA.
AC V4LN53;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=HECT domain-containing protein {ECO:0000259|PROSITE:PS50237};
GN ORFNames=EUTSA_v10010078mg {ECO:0000313|EMBL:ESQ45179.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ45179.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ45179.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
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DR EMBL; KI517435; ESQ45179.1; -; Genomic_DNA.
DR RefSeq; XP_006403726.1; XM_006403663.1.
DR AlphaFoldDB; V4LN53; -.
DR STRING; 72664.V4LN53; -.
DR EnsemblPlants; ESQ45179; ESQ45179; EUTSA_v10010078mg.
DR GeneID; 18021661; -.
DR Gramene; ESQ45179; ESQ45179; EUTSA_v10010078mg.
DR KEGG; eus:EUTSA_v10010078mg; -.
DR eggNOG; KOG4427; Eukaryota.
DR OMA; FVQGLDC; -.
DR OrthoDB; 1386at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PANTHER; PTHR45700:SF9; E3 UBIQUITIN-PROTEIN LIGASE UPL7; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
DR PROSITE; PS50096; IQ; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 799..1143
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 565..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 1111
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 1143 AA; 128749 MW; 31819EE84C3EF1DB CRC64;
MDLNRKHKVS LRGASSGEIS RDALLAKVSQ ERELRNYARR ANAAALFIQR VWRSYIVRKM
EAIELREEWE NSLSCRSDTL TKSWVSSRVL RPFLFFIRSL SVQHQKIQAR DILCMQTCFK
ILLESINSND QGYNFCSLAV GTFEESKTWA CQTRKLVYLC SFLLMESSYS QERIKDVLGV
SALVLRILIA LTDPKSWKII TKDNFKDAET AGNMIIQFIG SCKSGYYTAV RRYIKTLTKH
TDERLLITTS AVTLAVRPFH ARQPAFVDDS QPDTNLAVEE YVSLILTIPR LVCCLPSALI
RALKHKSILM PSFHTILILR DKILTRISEI EHSEKQSCTM EIPSVGWAIG NIISLATVSE
TDFMDPQESN PEMFYVLYVH VIVTLAKNLL SRVENVGIQD MHLDFEATSD ETGKGENTAK
ISFVELLQPV CKQWHLAKLL AVSGKDIRVI ADKGASASSK KVSETLELFD IARFYSCMLR
IFCVLNPVVG PLPVLNMLSF CPGYIVSLWS SLESVLFPEN GSIADNSSHG PVKTSWSTRS
PSENKLKHLK NDGFNKWVNV LNKFSGKSPG PRERVECASD QPESSQVKGS TDDVWDVETL
RGGPVGISKD VACLLQLFCA TYAHLLVVLD DIQFYEKQVP FMLEKQRRIA SMLNTLVYNG
LLRGTGPENR QLMDSAIRCL HLLYERDCRH PFCPSALWLS PGRTSRPPIA FAARTHEVLP
GSDVHTSPSM GSVITITPHA FPFEERVHVF REFISMDKAS RKMAGEVDAP GARSIEIVVR
RGHVVEDGFR QLNSIGSRLK SSIHVSFVNE SGLPEAGLDY GGLSKEFLTD ITKAAFATEY
GLFSQTTTSD RLLVPSPSAR HLENGIQMIE FLGRIVGKAL YEGILLDYSF SHVFIQKLLG
RYSFIDELSG LDPELYRNLM YIKQYDGDLK ELCLDFTVTE EFCGKMSIIE LKPGGKDISV
TNENKMQYIH AMADYKLNRQ IVPFSNAFYR GLTDLISPAW LKLFNAHEFN QLLSGGNHDI
DVDDLRRNTK YTGGYTDSSR TIKIFWEVMK GFEPSERCML LKFVTSCSRA PLLGFKYLQP
TFIIHKVSCD TSLWAAIGGQ DVERLPSAST CYNTLKLPTY KRASTMREKL LYAITSNAGF
ELS
//
