ID V4M2X3_EUTSA Unreviewed; 404 AA.
AC V4M2X3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10020854mg {ECO:0000313|EMBL:ESQ49232.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ49232.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ49232.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
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DR EMBL; KI517408; ESQ49232.1; -; Genomic_DNA.
DR RefSeq; XP_006407779.1; XM_006407716.1.
DR AlphaFoldDB; V4M2X3; -.
DR STRING; 72664.V4M2X3; -.
DR EnsemblPlants; ESQ49232; ESQ49232; EUTSA_v10020854mg.
DR GeneID; 18024742; -.
DR Gramene; ESQ49232; ESQ49232; EUTSA_v10020854mg.
DR KEGG; eus:EUTSA_v10020854mg; -.
DR eggNOG; KOG0703; Eukaryota.
DR eggNOG; KOG1030; Eukaryota.
DR OMA; ICTQCAG; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR CDD; cd08204; ArfGap; 1.
DR CDD; cd04038; C2_ArfGAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR044518; ARF_GAP_AGD11/12/13.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR PANTHER; PTHR46220:SF2; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD11-RELATED; 1.
DR PANTHER; PTHR46220; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD12; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF00168; C2; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50004; C2; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..404
FT /note="Arf-GAP domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004721396"
FT DOMAIN 65..187
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT DOMAIN 231..345
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 404 AA; 44928 MW; 865DDCF743C75B8D CRC64;
MSHLFSQHSR LLIASALVFE MSLGQENVDP VEVSGSHACL YDLLRSETPK GTPQKDLQTS
SSDPRDRLEK LLKQPGNKYC ADCGSPEPKW VSLSLGVFIC IKCSGVHRSL GVHISKVLSV
KLDEWTDDQV DTLVGYGGNT AVNQRFEACN IDQSKKPKPD STNEERNDFI RKKYEQHQFM
DPKDGALCPY QQQASRVNNS PPSLCSASHR STKNRIGHAF RNSWGRRESD HKGPKKSNSL
AGMVEFVGLI KVNVVKGTNL AVRDVMTSDP YVILSLGQQS VKTRVIKNNL NPVWNETLML
SIPEQMPPLK VLVYDKDTFS TDDFMGEAEI DIQPLVGAAK AYETSSIQEP MQLGSWVASK
ENTLVSDGII SLEEGKVKQD ISLRLQKVER GVLEIQLECL PLTQ
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