ID V4MDI7_EUTSA Unreviewed; 315 AA.
AC V4MDI7;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Metaxin {ECO:0000256|PIRNR:PIRNR038150};
GN ORFNames=EUTSA_v10022785mg {ECO:0000313|EMBL:ESQ50538.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ50538.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ50538.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- FUNCTION: Involved in transport of proteins into the mitochondrion.
CC {ECO:0000256|PIRNR:PIRNR038150}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC {ECO:0000256|PIRNR:PIRNR038150}.
CC -!- SIMILARITY: Belongs to the metaxin family.
CC {ECO:0000256|PIRNR:PIRNR038150}.
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DR EMBL; KI517392; ESQ50538.1; -; Genomic_DNA.
DR RefSeq; XP_006409085.1; XM_006409022.1.
DR AlphaFoldDB; V4MDI7; -.
DR STRING; 72664.V4MDI7; -.
DR EnsemblPlants; ESQ50538; ESQ50538; EUTSA_v10022785mg.
DR GeneID; 18026037; -.
DR Gramene; ESQ50538; ESQ50538; EUTSA_v10022785mg.
DR KEGG; eus:EUTSA_v10022785mg; -.
DR eggNOG; KOG3028; Eukaryota.
DR OMA; YFQTRCL; -.
DR OrthoDB; 1030843at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0001401; C:SAM complex; IEA:InterPro.
DR GO; GO:0007005; P:mitochondrion organization; IEA:InterPro.
DR GO; GO:0006626; P:protein targeting to mitochondrion; IEA:EnsemblPlants.
DR CDD; cd03193; GST_C_Metaxin; 1.
DR CDD; cd03054; GST_N_Metaxin; 1.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR017410; Metaxin1/3.
DR InterPro; IPR033468; Metaxin_GST.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR PANTHER; PTHR12289; METAXIN RELATED; 1.
DR PANTHER; PTHR12289:SF41; METAXIN-1 HOMOLOG; 1.
DR Pfam; PF17171; GST_C_6; 1.
DR Pfam; PF17172; GST_N_4; 1.
DR PIRSF; PIRSF038150; Metaxin; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787,
KW ECO:0000256|PIRNR:PIRNR038150};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 284..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..120
FT /note="Thioredoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17172"
FT DOMAIN 170..232
FT /note="Metaxin glutathione S-transferase"
FT /evidence="ECO:0000259|Pfam:PF17171"
FT REGION 238..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 315 AA; 35653 MW; 70D1B49FD2E82861 CRC64;
MEGDQQSADF TLVTRKPGFG LPTACPNCLP AYIYLKLAQL PFELAFNSTF PDSDELPYFE
SGTYVAYNNE DGGVIEKLKK DGIVNLDSQL QSLPDYLSLK ALIVSWLEEA LTYELWVGTE
GISVSKIYYS DIPWVISKVL FYKQTYIAKN SLGITKENAE QKEKLIYKRA SEAYEALSTR
LGEQKFLFED RPSSLDAFFL SHMLFIIQVL PETSVLRCKL LEHSNLVRYA EKLKSEFLEG
SSSSPSPPLH SFPSSFSRKG SKPKSKPKTE KTEEEKKFKK RAKFFVAAQF LAVVLYLSVM
GGGSSNELEY EDEDY
//
