ID   V4MEK3_EUTSA            Unreviewed;       848 AA.
AC   V4MEK3;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Homing endonuclease LAGLIDADG domain-containing protein {ECO:0000259|Pfam:PF03161};
GN   ORFNames=EUTSA_v10022548mg {ECO:0000313|EMBL:ESQ50953.1};
OS   Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX   NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ50953.1, ECO:0000313|Proteomes:UP000030689};
RN   [1] {ECO:0000313|EMBL:ESQ50953.1, ECO:0000313|Proteomes:UP000030689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA   Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA   Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA   Mitchell-Olds T., Schumaker K.S., Wang X.;
RT   "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL   Front. Plant Sci. 4:46-46(2013).
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DR   EMBL; KI517392; ESQ50953.1; -; Genomic_DNA.
DR   RefSeq; XP_006409500.1; XM_006409437.1.
DR   AlphaFoldDB; V4MEK3; -.
DR   STRING; 72664.V4MEK3; -.
DR   EnsemblPlants; ESQ50953; ESQ50953; EUTSA_v10022548mg.
DR   Gramene; ESQ50953; ESQ50953; EUTSA_v10022548mg.
DR   KEGG; eus:EUTSA_v10022548mg; -.
DR   eggNOG; KOG4197; Eukaryota.
DR   OMA; MESYAQR; -.
DR   Proteomes; UP000030689; Unassembled WGS sequence.
DR   GO; GO:0009507; C:chloroplast; IEA:GOC.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0010239; P:chloroplast mRNA processing; IEA:EnsemblPlants.
DR   GO; GO:0000373; P:Group II intron splicing; IEA:EnsemblPlants.
DR   GO; GO:0048564; P:photosystem I assembly; IEA:EnsemblPlants.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:EnsemblPlants.
DR   Gene3D; 3.10.28.10; Homing endonucleases; 2.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004860; LAGLIDADG_2.
DR   InterPro; IPR002885; Pentatricopeptide_rpt.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   NCBIfam; TIGR00756; PPR; 2.
DR   PANTHER; PTHR47539; PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN OTP51, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR47539:SF1; PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN OTP51, CHLOROPLASTIC; 1.
DR   Pfam; PF03161; LAGLIDADG_2; 1.
DR   Pfam; PF01535; PPR; 4.
DR   SUPFAM; SSF81901; HCP-like; 1.
DR   SUPFAM; SSF55608; Homing endonucleases; 1.
DR   PROSITE; PS51375; PPR; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          455..489
FT                   /note="PPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT   REPEAT          524..558
FT                   /note="PPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT   DOMAIN          626..788
FT                   /note="Homing endonuclease LAGLIDADG"
FT                   /evidence="ECO:0000259|Pfam:PF03161"
FT   REGION          806..834
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        813..834
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   848 AA;  97254 MW;  43CAA2D12CEEE6B0 CRC64;
     MTKTNGRDAT TMIVSGARGF SSPLSVASSS SAAVTVNVTS FNVSSLSFNL NIIPCYLVRH
     CSSSSSILLR PLSFSLLRHR SIYSRRSLRR LSFHGNQKPS FSQANSTAQR SVTFFEHVAG
     IKESREKTID FGDLESARND ARNFATRRVE TDVEVRELED LPEEWRRSKL AWLCKEAPSH
     KAVTLVRLLN AQKKWVRQED ATYIALHCMR IRENETGFRV YRWMTQQNWY VFDFGLATKL
     ADFLGKERKF TKCREVFDDI LNQGRVPSES TFHILVVAYL SSSEQGCLEE ACSVYNRMIQ
     LGGYKPRLSL HNSLFRALVS KQGVPSSDDL KQAEFIFHNV LTTGLELQKD VYTGLIWLHS
     CQDEVDIDRI NSLREEMKEA DFRESKEVVV SLLRAYAKEG SVEEVEKTWL ELLDLDCGIP
     SQAFVYKMEA YSKVGDSAKA LEIFREMEKY LGGATVSGYH KIIEVLCKVQ QVELAESLLK
     EFVESGKKPL LPSYIEIVKM YFVLGLHEKL EMAFVECLEK CQPSQTIYNI YLDSLVKIGS
     LEKAGDVFDE MKSNGTINVN ARSCNTLLKG YLDSENHVKA KKIYELMSLK KYEIEPPLME
     KLDYILSLVR KEVKKPLSMK LSKEQREVLV GLLLGGLQIE SDKEMKSHKI KFEFRDNSQA
     HVILRQHIHD QFREWLAPSS DLQEDIPFNF SSVSHSYFGF YAEHFWPKGR SEIPKLIHRW
     LSPHSLAYWY MYSGFKTSSG DIILRLKGSL EGVEKVVKAL RGKSMECRVK KKGKVFWIGL
     QGTNSAWFWK LIEPHVLEEM KDHLKPASES MNNDGDEEQS INFDTSSDNS SDDRIDYTYQ
     MKVNNVEV
//