ID V4MND9_EUTSA Unreviewed; 310 AA.
AC V4MND9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00012526};
DE EC=2.7.7.60 {ECO:0000256|ARBA:ARBA00012526};
GN ORFNames=EUTSA_v10004647mg {ECO:0000313|EMBL:ESQ33066.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ33066.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ33066.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- PATHWAY: Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis
CC via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-
CC phosphate: step 2/6. {ECO:0000256|ARBA:ARBA00004787}.
CC -!- SIMILARITY: Belongs to the IspD/TarI cytidylyltransferase family. IspD
CC subfamily. {ECO:0000256|ARBA:ARBA00009789}.
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DR EMBL; KI517748; ESQ33066.1; -; Genomic_DNA.
DR RefSeq; XP_006395780.1; XM_006395718.1.
DR AlphaFoldDB; V4MND9; -.
DR STRING; 72664.V4MND9; -.
DR EnsemblPlants; ESQ33066; ESQ33066; EUTSA_v10004647mg.
DR GeneID; 18012077; -.
DR Gramene; ESQ33066; ESQ33066; EUTSA_v10004647mg.
DR eggNOG; ENOG502QUUE; Eukaryota.
DR OMA; TPMLIHA; -.
DR OrthoDB; 1214813at2759; -.
DR UniPathway; UPA00056; UER00093.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0050518; F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0019288; P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; IEA:UniProtKB-UniPathway.
DR CDD; cd02516; CDP-ME_synthetase; 1.
DR HAMAP; MF_00108; IspD; 1.
DR InterPro; IPR001228; IspD.
DR InterPro; IPR034683; IspD/TarI.
DR InterPro; IPR018294; ISPD_synthase_CS.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR00453; ispD; 1.
DR PANTHER; PTHR32125; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR32125:SF4; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR Pfam; PF01128; IspD; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS01295; ISPD; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 310 AA; 34515 MW; EF2C9C6E1E9FB650 CRC64;
MAMLQANLGF VKSPTFPFSS SSFSCPKIAV KATSASLGFK NRSSVQRLDF SKRVSRIYRR
DALLLSIKCS SSAEFDNSNT VVKEKSVSVI LLAGGQGKRM KMSMPKQYIP LLGQPIALYS
FFTFSRMPEV KEIVVVCDPF FRDYFGEYEE TIDVDLKFAL PGKERQDSVH SGLQEIDVNS
ELVCIHDSAR PLVDTEDVKK VLKDGLAVGA AVLGVPAKAT IKEVNSDSLV VKTLDRKTLW
EMQTPQVIKP ELLKRGFELV KREGLEVTDD VSIVEYLKHP VYVTQGSYTN IKVTTPDDLL
LAERILSMDS
//
