ID V4MX09_EUTSA Unreviewed; 936 AA.
AC V4MX09;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Vacuolar protein sorting-associated protein 11 homolog {ECO:0000256|PIRNR:PIRNR007860};
GN ORFNames=EUTSA_v10002393mg {ECO:0000313|EMBL:ESQ36946.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ36946.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ36946.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- FUNCTION: Involved in regulating membrane fusion at the tonoplast and
CC the prevacuolar compartment. {ECO:0000256|PIRNR:PIRNR007860}.
CC -!- SUBUNIT: Core component of at least two putative endosomal tethering
CC complexes, the homotypic fusion and vacuole protein sorting (HOPS)
CC complex and the class C core vacuole/endosome tethering (CORVET)
CC complex. {ECO:0000256|PIRNR:PIRNR007860}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000256|PIRNR:PIRNR007860};
CC Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR007860}.
CC Prevacuolar compartment membrane {ECO:0000256|PIRNR:PIRNR007860};
CC Peripheral membrane protein {ECO:0000256|PIRNR:PIRNR007860}.
CC -!- SIMILARITY: Belongs to the VPS11 family.
CC {ECO:0000256|ARBA:ARBA00007070, ECO:0000256|PIRNR:PIRNR007860}.
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DR EMBL; KI517609; ESQ36946.1; -; Genomic_DNA.
DR RefSeq; XP_006418510.1; XM_006418447.1.
DR AlphaFoldDB; V4MX09; -.
DR STRING; 72664.V4MX09; -.
DR EnsemblPlants; ESQ36946; ESQ36946; EUTSA_v10002393mg.
DR GeneID; 18013938; -.
DR Gramene; ESQ36946; ESQ36946; EUTSA_v10002393mg.
DR KEGG; eus:EUTSA_v10002393mg; -.
DR eggNOG; KOG2114; Eukaryota.
DR OMA; ENECPAC; -.
DR OrthoDB; 5491867at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0033263; C:CORVET complex; IEA:UniProtKB-UniRule.
DR GO; GO:0030897; C:HOPS complex; IEA:UniProtKB-UniRule.
DR GO; GO:0009705; C:plant-type vacuole membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd16688; RING-H2_Vps11; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR016528; VPS11.
DR InterPro; IPR024763; VPS11_C.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23323:SF24; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG; 1.
DR Pfam; PF00637; Clathrin; 1.
DR Pfam; PF12451; VPS11_C; 1.
DR Pfam; PF17122; zf-C3H2C3; 1.
DR PIRSF; PIRSF007860; VPS11; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50236; CHCR; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR007860};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Vacuole {ECO:0000256|PIRNR:PIRNR007860};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 847..882
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT COILED 804..838
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 936 AA; 106548 MW; 3C1E36227ABC7F54 CRC64;
MYQWRKFDFF EEKYGGKIPE DVTGEIQCCS SGRGKVVIGS DDGSVSFLDR GIKFDSGFQA
HSSSVLFLQH LKQRNFLVTV GEDEQISPQQ SGMCLKVFDL DKAQEESTSS SAPECIGILR
IFTNQFPEAK ITSFLVLEEV PPIVLIAIGL DNGCIYCVKG DIARERITRF KLQVDGVSEK
KRSPITGLGF RLDGLSLLLF AVTPDSVNSF NLQAQPPKLQ TLDHIGSGVN TVTMSDLAEL
IVGRPEAVYF YEVDGRGPCW AFEGEKKFMG WFRGYLLCVI ADPKNGTNVF NVYDLRNRLI
AYSLVVDKVS NMLCEWGNII LITADKSLLC VTEKDMESKL DMLFKKNLYT VAINLVQSQH
ADAAATANVM RKYGDHLYGK QDYDEAMSQY INTIGHLEPS FVIQKFLDAQ RIYNLTNYLE
KLHEKGLASK DHTTLLLNCY TKLKDVEKLN TFIRKEDGIG ELKFDVETAI RVCRAANYHE
HAMYVAKKAG KHEWYLKILL EDLGNYDEAL QYISSLEPSQ AGVTIKEYGK ILIEHKPKEA
IDILMRLCTE QGTSNGVYLS MLPSPVDFIN VFVQHPHSLM EFLERYIEIV KDSPAQAEIN
NTLLELYLSR DLNFPSISQS ENGLDQDFTD QSVLASVSKA DYEKRKIADS KDIMEKDFIE
RQQKGLELLK MAWPSDQEQP LYDVDLAIIL CEMNSFKEGL LYLYEKMKLY KEVIACYMQN
HDHEGLIACC KRLGDSRKGG EPSLWADLLK YFGEIGEDCT KEVKEVLTYI ERDDILPPII
VLQTLAKNPC LTLSVIKDYI ARKLEQESKI IEEDRRAVEK YQETTKNMRK EIEDLRTNAK
IFQLSKCTAC TFTLDIPAVH FMCMHSFHQR CLGDNEKECP ECAPEYRSVM EMKRSLEQNS
KDQDLFFQQV KSSKDGFSVI AEYFGKGIIS KTTDEN
//
