GenomeNet

Database: UniProt
Entry: V4RRQ2_9RHIZ
LinkDB: V4RRQ2_9RHIZ
Original site: V4RRQ2_9RHIZ 
ID   V4RRQ2_9RHIZ            Unreviewed;       507 AA.
AC   V4RRQ2;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   05-JUL-2017, entry version 28.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=N177_1175 {ECO:0000313|EMBL:ESR25840.1};
OS   Lutibaculum baratangense AMV1.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhodobiaceae; Lutibaculum.
OX   NCBI_TaxID=631454 {ECO:0000313|EMBL:ESR25840.1, ECO:0000313|Proteomes:UP000017819};
RN   [1] {ECO:0000313|EMBL:ESR25840.1, ECO:0000313|Proteomes:UP000017819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AMV1 {ECO:0000313|EMBL:ESR25840.1,
RC   ECO:0000313|Proteomes:UP000017819};
RX   PubMed=25059877;
RA   Singh A., Sreenivas A., Sathyanarayana Reddy G., Pinnaka A.K.,
RA   Shivaji S.;
RT   "Draft Genome Sequence of Lutibaculum baratangense Strain AMV1T,
RT   Isolated from a Mud Volcano in Andamans, India.";
RL   Genome Announc. Announc.2:e00735-14(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ESR25840.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AWXZ01000017; ESR25840.1; -; Genomic_DNA.
DR   EnsemblBacteria; ESR25840; ESR25840; N177_1175.
DR   PATRIC; fig|631454.5.peg.1160; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000017819; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000017819};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017819}.
FT   DOMAIN      196    337       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      412    481       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     204    211       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   507 AA;  56209 MW;  11856EEA05F33184 CRC64;
     MATGRWAGST RDDCQASDAE GSGAEDAPGT TEAVWARIVE RIRQEYGEDV YRSWFKGVAV
     VEADEFTVHL SVPTQFLRMW LRNNYGTRLL ALWRAERPSV QRVDIRVRGV ATVPACEKAP
     AEPRRAAARD ALKVVEPSGE VRPPRVELPA GEAGGLESAP LDPRFRFDSF ATGDSNKIAH
     DTAFAVAAAA ASGETLFNPL FIHGGVGRGK THLLHAIAWR TKELGPGRRV LHLSAEQFVF
     RFVSALRADS AIDFKDRLRQ VDLLLIDDLQ FLQGKATHRE FGHTMNALIE ACRQVVIVAD
     RSPAELEGFD ERTRSRLAGG LVAGVGQQEF VLRRRILEAR AAALGRQGQR VDLPDEVLEY
     VAKNVSSNGR ELEGAINRLA AHQCYAGVPV TVELAEKVIR DLVSQHERAP VKIEDIQRVV
     SSHYQLSRQD LVSSRRNRAI VLPRQVAMYL AKTMTPRSLP EIGRRFGNRD HTTVLHAIRK
     IEKLLGSDGN LARDVETLKR RVEDGEA
//
DBGET integrated database retrieval system