ID V4XCW6_9ARCH Unreviewed; 769 AA.
AC V4XCW6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Putative hydrophobe/Amphiphile Efflux-3 (HAE3) family protein {ECO:0000313|EMBL:ESS05794.1};
GN ORFNames=A07HB70_01923 {ECO:0000313|EMBL:ESS05794.1};
OS uncultured archaeon A07HB70.
OC Archaea; environmental samples.
OX NCBI_TaxID=1412872 {ECO:0000313|EMBL:ESS05794.1, ECO:0000313|Proteomes:UP000030648};
RN [1] {ECO:0000313|Proteomes:UP000030648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24335829;
RA Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA Heidelberg K.B., Banfield J.F., Allen E.E.;
RT "Seasonal fluctuations in ionic concentrations drive microbial succession
RT in a hypersaline lake community.";
RL ISME J. 0:0-0(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI543182; ESS05794.1; -; Genomic_DNA.
DR AlphaFoldDB; V4XCW6; -.
DR STRING; 1412872.A07HB70_01923; -.
DR PATRIC; fig|1412872.3.peg.1998; -.
DR Proteomes; UP000030648; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR022813; SecD/SecF_arch_bac.
DR InterPro; IPR000731; SSD.
DR NCBIfam; TIGR00921; 2A067; 1.
DR PANTHER; PTHR30081:SF10; PROTEIN EXPORT MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR30081; PROTEIN-EXPORT MEMBRANE PROTEIN SEC; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030648};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 190..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 608..625
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 706..726
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 732..758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 211..339
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 638..757
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 349..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..382
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 769 AA; 81595 MW; F91010638B940BAD CRC64;
MISSAFATLG AVIERHPLVT LGVALVLLVA AFGGAAQITS VTGNDAFTAE NPTLERFQDT
FDRSTVAVLV RGQVTDPRTM RAIDRFDRRL SARENVQTVT SPADRVRAAY GEIPGDEERI
ARVVGNEDTV FVTIVLDTGL SQEEQRPVYT DAVDASEWAQ FPAGVDVIVT GQAAFSSQLS
AAIQSSTQQQ LGLAVGLMIV ALFFLFRGVR LRLLPVVAVF VGVIYTFGAI GYAGIPNSTL
TSAVFPILIG LGIDYSVQFH ERYEEELARA PPREALPRAL SAIGPAVFIA MLAAALGFGA
TWISTLDSPA FVWFAQTSIF GVILTFLTAL IVLTPVLTIW ARVRGRYGGQ DPKTRAATAA
DGGERVDDTE REPADGPTDD PDRPAPADGV SAADEGDTPG RFGRALGTGS RALASHPVLV
LVLAALLTTG GVQASTQLDT LADTEEFIPQ DLPALLDLEQ FRAQTGGGSA VQFDVLVAGG
VTQPETLRWM EQFDRVAMGT PSVVGVETPA EVVMRHNDGR IPETEAGVER ALARAPATER
QRFVDDGYGR IVVVSRPDLS TEGTLSFISN VRSALQFSQP PPGVDAQLTG TDVVSTPSTL
DQIESRNTTT VLGFGFVFVA LLLYYRDLTR AIAPVVPMAF VVGWQGLYMY GLGIRVSPLG
ASLGALTVGI GAEYTVIVME RYYEEVEQGA SPLDAVETAA TRVGKAISVS GMTTVFGFSA
LAASPFPIIA DFGFLTVGVI ALTLVAALAT LPPTLVILDR IERAVGRRA
//
