ID V4XDG2_9ARCH Unreviewed; 879 AA.
AC V4XDG2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Superfamily I DNA and RNA helicase {ECO:0000313|EMBL:ESS06029.1};
GN ORFNames=A07HB70_01576 {ECO:0000313|EMBL:ESS06029.1};
OS uncultured archaeon A07HB70.
OC Archaea; environmental samples.
OX NCBI_TaxID=1412872 {ECO:0000313|EMBL:ESS06029.1, ECO:0000313|Proteomes:UP000030648};
RN [1] {ECO:0000313|Proteomes:UP000030648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24335829;
RA Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA Heidelberg K.B., Banfield J.F., Allen E.E.;
RT "Seasonal fluctuations in ionic concentrations drive microbial succession
RT in a hypersaline lake community.";
RL ISME J. 0:0-0(2013).
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DR EMBL; KI543181; ESS06029.1; -; Genomic_DNA.
DR AlphaFoldDB; V4XDG2; -.
DR STRING; 1412872.A07HB70_01576; -.
DR PATRIC; fig|1412872.3.peg.1647; -.
DR Proteomes; UP000030648; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF8; HELICASE WITH ZINC FINGER 2; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ESS06029.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ESS06029.1};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030648}.
FT DOMAIN 93..321
FT /note="PD-(D/E)XK endonuclease-like"
FT /evidence="ECO:0000259|Pfam:PF12705"
FT DOMAIN 508..594
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 606..674
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 678..861
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
SQ SEQUENCE 879 AA; 96375 MW; AE593A0EB407A8EF CRC64;
MNLRGPITSV GDVRTVDTEY GSRDLVETTV RPDRGAADPV TVTLWGKWTH TADHAEPGME
LLVTDAERDD HGYATTGDSY VVLEPEFLVD VTDVRGWVQC PRIYYLNKLS GVPLKYPVVK
GTLVHEVFGD LLRGVDLDDA VDDRVAEAGL ELGLLGRDAA AVRDEVRRNA AAIEGWLAQG
ALGETDDWRS ERTLVSPTFG LKGRADAVRR GAPVELKTGK NTKREPRFHD KMQAACYALV
LDEHDEGADT ATLLYTKNAT LDRGEASGDL SPAKEFSVGR GLKEFAVRTR NEIAAMEFST
VVPTGYEADA KCEYCFERDS CMVVAGRLGQ ESKAGTVGDP LPQAERDYFE RFYGHIEAER
RTAHAEYRKL WEQSAAERAD ADRALVGLVP TDTEQRPDGR WELRARRPGS SVSKLREGDV
ALASEGDPVG GRSEMARIER LGDEVVVTAD EPLDLCRLDV YPSEISVDRM LRALHDFALK
RDESRRDLIL GRRAPAFGDV DETFVDNNES QDEAVRRAVA AEDCALVHGP PGTGKTYTIA
RLVRALVARG DRVLLAAFTN RAVDNALAAL RDQGFEDVVR YGTETGVRDD MRDVRLVARG
DPDERAAALG DAPVVAATTS GCISRTLTEE AFDVAVVDEA SQLTEPGTLA ALNRAERFVL
VGDHEQLPPV VRSETDLRTS LFERLVDEHP AASVMLNRQY RMCQRIQAFP SREFYDGALR
PATAAVARRR VGDLPGVDPD ALPASLRDPV SFVDPDGRRE GNVNRAEAAR VAAVVDAFLA
AGVDPDDVVV IAPFRAQVAR IAERVDVTVD TVDRFQGSSE EVVVVSFVAT GTLDGPIFED
HRRVNVALTR AKRALVLVGD ADALGSEPFY RRMLDWARR
//
