ID V4XKP8_9ARCH Unreviewed; 312 AA.
AC V4XKP8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=BirA, biotin-[acetyl-CoA-carboxylase] ligase region {ECO:0000313|EMBL:ESS08914.1};
GN ORFNames=A07HN63_01122 {ECO:0000313|EMBL:ESS08914.1};
OS uncultured archaeon A07HN63.
OC Archaea; environmental samples.
OX NCBI_TaxID=1412873 {ECO:0000313|EMBL:ESS08914.1, ECO:0000313|Proteomes:UP000030667};
RN [1] {ECO:0000313|Proteomes:UP000030667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24335829;
RA Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA Heidelberg K.B., Banfield J.F., Allen E.E.;
RT "Seasonal fluctuations in ionic concentrations drive microbial succession
RT in a hypersaline lake community.";
RL ISME J. 0:0-0(2013).
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DR EMBL; KI543214; ESS08914.1; -; Genomic_DNA.
DR AlphaFoldDB; V4XKP8; -.
DR STRING; 1412873.A07HN63_01122; -.
DR PATRIC; fig|1412873.3.peg.1208; -.
DR Proteomes; UP000030667; Unassembled WGS sequence.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16442; BPL; 1.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_00978; Bifunct_BirA; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR030855; Bifunct_BirA.
DR InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR InterPro; IPR003142; BPL_C.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00121; birA_ligase; 1.
DR PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR Pfam; PF02237; BPL_C; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR Pfam; PF08279; HTH_11; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ESS08914.1}.
FT DOMAIN 62..251
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51733"
SQ SEQUENCE 312 AA; 33309 MW; CB002687FC4EF62D CRC64;
MNETRRQLLA ALSDGPVDGP NLADDLGVSR AAVWKQVEAL REAGFAVEST PDGYAVREVP
DYGAAAIEYD LDAPYRIEYH DAIESTNDRA RELAGAGNHD IAVVADEQTG GRGRLDRSWA
SPSGGLWCSL VLQPSLPAAH SPLVTLAAGV AVVDACRAAG VEAALKWPND ILVGDGGDRG
GRKLAGILTE MEGEADRVSW LLVGIGLNAN IDAAELPDDA TSLRAEVGDV DRRRLIQTVL
ESIAELLTDG ERVIEQWREY SSTLGQHVRV ETHRDTVEGR AVDVRFPGAL VVETATGEQV
VHAGDCEHLR PA
//
