ID   V4YDT0_9ARCH            Unreviewed;       845 AA.
AC   V4YDT0;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=A07HN63_00934 {ECO:0000313|EMBL:ESS09302.1};
OS   uncultured archaeon A07HN63.
OC   Archaea; environmental samples.
OX   NCBI_TaxID=1412873 {ECO:0000313|EMBL:ESS09302.1, ECO:0000313|Proteomes:UP000030667};
RN   [1] {ECO:0000313|Proteomes:UP000030667}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24335829;
RA   Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA   Heidelberg K.B., Banfield J.F., Allen E.E.;
RT   "Seasonal fluctuations in ionic concentrations drive microbial succession
RT   in a hypersaline lake community.";
RL   ISME J. 0:0-0(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; KI543205; ESS09302.1; -; Genomic_DNA.
DR   AlphaFoldDB; V4YDT0; -.
DR   STRING; 1412873.A07HN63_00934; -.
DR   PATRIC; fig|1412873.3.peg.1002; -.
DR   Proteomes; UP000030667; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 1.
DR   CDD; cd00156; REC; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR   PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR   Pfam; PF13185; GAF_2; 2.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF13188; PAS_8; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00065; GAF; 2.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ESS09302.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          8..124
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          313..386
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   COILED          113..140
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   845 AA;  94187 MW;  5697AA661172D827 CRC64;
     MSGTAGIDVL HVDDDPDFVD VAADILEEEC GDFTVETATS ASEGLDRLAA DDFDCVVSDH
     MMGGQNGIEF LRAIRERDSD LPFILFTGKG SEGVASDAIS AGATDYLQKQ IGNDQYTVLA
     NRIENAVEQH RAQQRATKLE RIRALTSDVN QALMRADSRS MAKTRVCEII SDSDPYLFAW
     IGEVDADTQE IRPQASAGVE EGYLDDITVT ADDTPTGHGP GGTAIRERRV AVTQNISEDQ
     QFEEWREEAV ARDYQAVAAV PLEHQERLYG ELVVYAEQPH AFNDREQELL ADLGRDIGNA
     IHSLALQEDL RTQQNRQRAL FENAPNSVIA CDKAGSSHRI VNVNHAFEET FGYTAEEIIG
     TDVADILVPD DGMVAHDQFR ERVETGESIT TEVERITADG PREFLLHVIP YGVAGDTIEG
     TYAWYMDITD RKQREREIDR RNSILRTILE NLPMGVLVED ADSDILMAND QLCDIFDVPL
     TGDELIGRDC DSAAEQIKDR FADPEAFIAG VGERHANREM VHNEELRLDD GRTVERDYLP
     YSLPEGDANM WVYRDITTRK KYEQTLKELI ASTQDLQSAT TPAEVATIGA ETAKGVFDRP
     INGVHLYDES DDELKPVSWT GAVEEQLGAE PPALPVEDSL AGQVYRTKDR KSYGNIAEQP
     EQFASETPFQ SELICPLGDH GVFILSATEP DAFDQVDETL AQLLSTSLTT ALNRVEQRQQ
     LETKNERLDE FASVLSHDLR NPLNVAEGRL ELAQGEFDSE HFAPIERSHT RMRSLIESLL
     ALARKGNDIG EFEPVDLDSF AQKCWRNVDT EQATLETTTD QTIQADRNQL KQLLENLRSK
     CGRTR
//