ID V4ZAY6_TOXGV Unreviewed; 2023 AA.
AC V4ZAY6; A0A0F7UTN1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Gamma-tubulin complex component 4, putative {ECO:0000313|EMBL:CEL71796.1};
DE SubName: Full=Spc97 / Spc98 family protein {ECO:0000313|EMBL:ESS29557.1};
GN ORFNames=BN1205_038550 {ECO:0000313|EMBL:CEL71796.1}, TGVEG_209970
GN {ECO:0000313|EMBL:ESS29557.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS29557.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS29557.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS29557.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS29557.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS29557.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL71796.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL71796.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SIMILARITY: Belongs to the TUBGCP family.
CC {ECO:0000256|ARBA:ARBA00010337}.
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DR EMBL; LN714490; CEL71796.1; -; Genomic_DNA.
DR EMBL; AAYL02000295; ESS29557.1; -; Genomic_DNA.
DR STRING; 432359.V4ZAY6; -.
DR EnsemblProtists; ESS29557; ESS29557; TGVEG_209970.
DR VEuPathDB; ToxoDB:TGVEG_209970; -.
DR eggNOG; KOG2065; Eukaryota.
DR OMA; FEWESAF; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005815; C:microtubule organizing center; IEA:InterPro.
DR GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR Gene3D; 1.20.120.1900; Gamma-tubulin complex, C-terminal domain; 1.
DR InterPro; IPR007259; GCP.
DR InterPro; IPR040457; GCP_C.
DR InterPro; IPR042241; GCP_C_sf.
DR InterPro; IPR041470; GCP_N.
DR PANTHER; PTHR19302; GAMMA TUBULIN COMPLEX PROTEIN; 1.
DR PANTHER; PTHR19302:SF27; GAMMA-TUBULIN COMPLEX COMPONENT 4; 1.
DR Pfam; PF04130; GCP_C_terminal; 1.
DR Pfam; PF17681; GCP_N_terminal; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000002226}.
FT DOMAIN 2..318
FT /note="Gamma tubulin complex component protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17681"
FT DOMAIN 1343..1641
FT /note="Gamma tubulin complex component C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04130"
FT REGION 353..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1311..1330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1543..1570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1651..1676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1692..1793
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1943..1968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..377
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..665
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..693
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1311..1329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1543..1565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1697..1722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1723..1737
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1738..1783
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2023 AA; 220171 MW; D2728915DE27B15A CRC64;
MMHDVLLALA GFPGDVFVYA PPGSSADASF SSSQLSASES PEAATRTGGL LLSPKLASFF
TPAEEELLNR IVVSGFHLIQ IRDFVSSVET DVPAVSLASA SSLFSLSSSG QEVKRSAKEK
HAGEESDGDQ VGFKGLYVSA LARAMDAEVQ EYLTKIVEIE AQVLLQPLLP LSAVYVLLAT
ERQKLATLYE IVTKIRSLAL MYRDPSPALS PSAFVVTASS LLPHSARHHV FQDSKTERGM
TPRRVSLPCG PLLDLLWAGT RSGNSLVQQV YRQVLDACVH VFIFQLSSWL LAGQLHDPFG
EFFLSRRSSL VPASSSSSSS SSSIFANLAV KQQNAKHVAP RRENASQAIA LSLSSSHGPA
PSSPSSPSPP SPSSPPSPSS LSSDSLFVYE NLTQPLSPSQ LCFEWESAFS LVAFRLPSCC
FPSPKLASPS ASGASLCSAT KSEQHPHASL VPSPAAAGTA LFVGRAVRIL TRSGLWGEAQ
VQQLKPLVAR MRRAFRHPSS PASVLLPCLE ILRRIVGRLL WELISEEAAL EDQLVLLHDF
FLLGHGHFFQ VFLDAATRCT RRHLSSSFAS AASLALMSST SRQATTFELQ LRRSWQQAIS
ETAFSSGSLS SSLNRTPNAK ETGVDDVPSR STTPVSGVTG GSVQREERSG DGGDTGRDGE
DSTAQMEDSA AHPGQRPAGL PTSSTSCISP RFSASPRAVS LVGSRPPTPK SARANPQSAC
RRSSSSPSSS SPSSSSSSSS SSSSSSSSSS SFSSSSSSSF SSSSCTASVN RRSLSCESVA
VRGPVVAQRV KRKNTFFIER RKVACAEQGK EEWTDAIHRS FRLRVLGRGF EVTDFCAESR
RAALVRHTEA RRASKARGCL NEDLCGFRTR DSPLQVGSQF LLRGLARVLE SGVLVLGEGG
ERLRQIDEKG TEADGVEDER APICPLSACL HADKQSITHG FKHSIQFRVS ALSSLPSPTT
EASRWLDSPG SSPDALQDPL GGGFAVVFQS SKTPASFRPL SARGSPKKTE TALVCAPGCP
LFWPAAGDCV AVEVRVAKVS RSVFRKTLDG GEEGEKEDFS ESLRTLQLDD EAVLVAELAV
FLGGKNAKNA FQQGSSSDYA PDGLFSSFAN SSVASAAPQT VCTSEAKPST DVYMLQRAQR
VWRLHACEDL GEELFSLKLH YLAEHHELRV YIQRAADSGA GQTRARLTEN EKKYQQPSLR
ERLQESPLLR VSLFDLSQAM TTEQGAAFVG LFSVPLLHRH RISPPSFFRA TQGETGRGRG
RGLVELPSSC VAMSLSDCPV IIQEWSHEAH PAPLQLPSLL FESSTSTSAS SAPCASASPP
SSWETRNDGD GGNSALAACL RGKPRTHAEL WQQLQLLFLP RWPTPLLIST RNLDCYNALF
QFLLEQRHLQ FELQRLWLDA GFIQKRLWRP RRRAGNRKPV SPRASSPCFL AEEDRDDEAT
ACWDGLWTLR ARMAFLLNHV LHHLLTVVVQ PAFRQLQSVV RDSEDFELVK CSHDSFLLQL
ASKCWLRLSS LLRPFLHSLQ SVRRFIDMFA LLVDRHTAAA AGTTHRGERK SWRRTAGDTR
GSQGEKSDLD LSANSVSGSL CFETVMSTSE WRVVRQKLRV IRDDLHRSLS AFFAELAALR
QNPLHAQLDA LMVDFDFNGF FSNLTGRGKL GDPLSTPSPQ PPLAVGASRV DPTRGASGLA
ASAAALSFFG GNRSSSRAVR EQRRPGERRP GTPRRGEPRQ VQGEDDEEEE ERLDEVEIED
GREGNYEEKG EGEEERERTM CSHSFRQEAD SEREARRRMP EQFSGAARDS GVRGQAAAIS
RGLTTSAYSS SGHPHAHSVV HKPFPLQRAA ASPVRGQPFT MASCQLPTSD PSDPVCSAPS
RSARLVTPPL PAPLFASFPE CGEDHGQKVS CQEGVGFDED PMRFRGRTTS VLRQASPSRF
FASEARQTEE RWSAYSAEEG RLRMRSAGEQ EDSEDLPNRP FNSSLDTATN VGMSQEGEVR
ETDGTRDAFY TDLQARARAA LREARERAAR RRLLQYQHDY CLP
//
