ID   V5A6V5_9ARCH            Unreviewed;       826 AA.
AC   V5A6V5;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Putative exporters of the RND superfamily {ECO:0000313|EMBL:ESS11285.1};
GN   ORFNames=A07HR60_01337 {ECO:0000313|EMBL:ESS11285.1};
OS   uncultured archaeon A07HR60.
OC   Archaea; environmental samples.
OX   NCBI_TaxID=1412874 {ECO:0000313|EMBL:ESS11285.1, ECO:0000313|Proteomes:UP000030679};
RN   [1] {ECO:0000313|Proteomes:UP000030679}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24335829;
RA   Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA   Heidelberg K.B., Banfield J.F., Allen E.E.;
RT   "Seasonal fluctuations in ionic concentrations drive microbial succession
RT   in a hypersaline lake community.";
RL   ISME J. 0:0-0(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KI543231; ESS11285.1; -; Genomic_DNA.
DR   AlphaFoldDB; V5A6V5; -.
DR   STRING; 1412874.A07HR60_01337; -.
DR   PATRIC; fig|1412874.3.peg.1540; -.
DR   Proteomes; UP000030679; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        229..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        254..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        421..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        642..663
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        670..692
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        698..716
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        746..769
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        781..799
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          257..380
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   DOMAIN          666..797
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   826 AA;  87910 MW;  92FD456945F79761 CRC64;
     MQAEQTLRRA SDYVVDHPTQ VIVVCLVLTA VFAPGMARLS TEAGTSQFTD GVPEADALEA
     VEDEFDPRFS ADEPTTQLIQ TGDNVLDRRG LLIMLETTER VEQRDNLRVA SSRSAASAVA
     QELDSEAETA AQQRAVIEDA TDAEIRQAVQ ALGDDPGFES LVGTEFNAEA AEATASLGVL
     THEFPREGGD TTAVQRQVQT IAERTDGDIT VFGSGILDDE FQNVVFDSLS IVVPVTLVVI
     LGLLAVAYRD PFDFALGGFA LLLAVVWTFG FTGWAGIPFS DMLVAVPVLL LAIGIDFGIH
     TVNRYREERT AGEDPAEAMR AATGQLVVAY SIITGTTVIG FLANLVSNLG PIQEFGIVAG
     VGIIFTLAIF GAFLPAAKLT IDRWRADNGI PSFGETPLGA EGSTLGEFLP RTRQLWGNAP
     VVFLLVVLLV TGGAASYGAG VDTTFDDEDF LPPQEQAAYI SYFPEPMQPA EYTVAATLDL
     LSERFETAEG DTVTVYIEGR MTDGHAIASM ARAERDPPDS FVERDGRART DSIVDPIDAL
     REDDEAFAER VAANSIGAPV PNRNLEGIYG DLRASRYEGF TNEYLSEDNR ATRVVYQVES
     DATDQQITAD ARAVAERYRG EAVATGQIVV FQAVADTIFQ SALLSLAAAL GLSSVFLVAL
     YGLLVGRASL GLVTLFPVLV AVCLLTATMR LLAIPFNALT GTILAITIGL GVDYAVHVSH
     RFYDEYEATG DPQQAVDIML RGTGGALTGT MATTALGIGV LVLAITPILG EFGRLTALSI
     TYAYLASILV LPAALVVWVR VVDEDETQQP TATGVAADGG GQTESS
//