ID V5AZ77_TRYCR Unreviewed; 1330 AA.
AC V5AZ77;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Paladin {ECO:0000256|ARBA:ARBA00040012};
GN ORFNames=TCDM_05183 {ECO:0000313|EMBL:ESS66180.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS66180.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS66180.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS66180.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the paladin family.
CC {ECO:0000256|ARBA:ARBA00037958}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS66180.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AYLP01000049; ESS66180.1; -; Genomic_DNA.
DR EnsemblProtists; ESS66180; ESS66180; TCDM_05183.
DR VEuPathDB; TriTrypDB:TCDM_05183; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR CDD; cd14496; PTP_paladin; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 3.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR23339:SF96; PALADIN; 1.
DR PANTHER; PTHR23339; TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE; 1.
DR Pfam; PF14566; PTPlike_phytase; 3.
DR SMART; SM01301; PTPlike_phytase; 3.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000017861}.
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1330 AA; 149969 MW; 8ED0E3BEAEA6B552 CRC64;
MARLWRKPHS HRKTALSPPT PLVMQVDNDR EVLELATLVY KFSTFEQQKG GNRATGGNNS
SQYDASGVVD PWRSFSSSIA FDPERSTTSM QLGRMSMRSS SVLRITDGTI ALMESLTNQR
DIVLPSPSEV GVVRSGDVLS ANHILVVDLQ DALRSHKWPT GIISGAPYFR IVPRLNVAGV
AQPNISAVRT VVNEVSRAYD GAFVWVNLRE EPLIYINDQA HIVRERKEPL NPMIIPNVTG
RGIAQIEEKL KQEVLKEAHE NGGNVSVHME GANGLMEDQW ESADPHCVLT LQNVFDALRP
NVIFYRRPIT RNVGPQPQDF DFVFNTCVEY PRAVIVFNCQ TGRGKTSSMM LIASIVRFYQ
MCGHDVSLDI RLLRSESRGF RFRTIRKLIS LIPDGKLHEH RLMILLELID KVYSITEHIH
AAFYTGTASA EEAMMHLQQY SYFLVFSFYC EQRLWNFNIK IPFSEWLAEN NELRLIIASI
QSMEDELREE CIVAPIAEGE AAWAASIVRH RRGNVLSAGR ILYTVPMLSE DSQHVNTLRQ
LAPDVPIFTC GRLSESGRNL LMAEVRQYFP NEGNILWINL RAEPMVYIND ISFTLSDYDT
ISGNSAELAS TMHVSLKAME QIEERLRRDV ILESQEHKGV ILLHHIEGNG KRSTIRVKVR
SVRTPKSTMA DFATEYGVSY HRIPIPFAGH MLASDVDPFL EYLSKKDGKH EVFIIHDSEG
SMRTTVALNM LTLYRASRAI SLRRLATPDE FREVLRVGQG GVVLPSAQVV SSVAVNPDEL
PKVPVELQLA ATICQMLTAG SLLRVVEAAI SLGGRGTRWN ILHMLNHLKV TMADAMNKVK
IMRNTVCLVR TYLLVLLSAI YIDSMGDYCL EKPFSDWVEE RTEVANIIAN LDQRAEQSIK
YVEHRTFMKG SVPHHNGDVL TANCMLKADH FPGCQKKGLR PELCGAPNFR KVDTINVYGV
AIPTLMGIHN ILSLLGASQE PLQAYPGENN DKEVHMGFAA PRLFEPRFSP EELSKPLRGS
VVWVNLREEP ILYVGDRPFV LRNLDAPYVN VELTGIAAHK VEHVETQLMV DVLKEATRHN
GMFLVSDEGE PGEIVGIWEP ATRETVKTVR EVYDELRAQG IRVTLLRLPV TDEQSPSAED
FDALVSELLP SIATHMDRRE TLSFVFNCQM GRGRTTTGMV ICCLLIGLVI PEYYDELNNR
YDPLFKPDDS PLSRGEYSCI VQLKRVLTGG RQAKLQVDLV LEVCAKMQNL RTAIESFALQ
VKSPDVTESQ RGRAHHHGVH YLRRYFNLIT FAAYLQEEYN SMKKMMRSTY SSWLAQRPEL
TTLCDSASLK
//
