ID   V5BF76_TRYCR            Unreviewed;       824 AA.
AC   V5BF76;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=CDC16 {ECO:0000313|EMBL:ESS66399.1};
GN   ORFNames=TCDM_05029 {ECO:0000313|EMBL:ESS66399.1};
OS   Trypanosoma cruzi Dm28c.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS66399.1, ECO:0000313|Proteomes:UP000017861};
RN   [1] {ECO:0000313|EMBL:ESS66399.1, ECO:0000313|Proteomes:UP000017861}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dm28c {ECO:0000313|EMBL:ESS66399.1,
RC   ECO:0000313|Proteomes:UP000017861};
RX   PubMed=24482508;
RA   Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA   Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT   "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL   Genome Announc. 2:e01114-13(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESS66399.1}.
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DR   EMBL; AYLP01000046; ESS66399.1; -; Genomic_DNA.
DR   EnsemblProtists; ESS66399; ESS66399; TCDM_05029.
DR   VEuPathDB; TriTrypDB:TCDM_05029; -.
DR   Proteomes; UP000017861; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR007192; APC8.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR   PANTHER; PTHR12558:SF10; CELL DIVISION CYCLE PROTEIN 23 HOMOLOG; 1.
DR   Pfam; PF04049; ANAPC8; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 2.
PE   4: Predicted;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017861};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          25..312
FT                   /note="Cdc23"
FT                   /evidence="ECO:0000259|Pfam:PF04049"
FT   REPEAT          460..493
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          494..527
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          119..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          337..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          659..685
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..151
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        337..356
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        665..685
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   824 AA;  91458 MW;  E1D171EF21AE5CD8 CRC64;
     MHRQESVSSG GGNATGRGSL TTAEVLDRAM NQCMQRGLFD TASWLGQLAL NATEXXXSVL
     RDSISATSPA VAALQDQPLT GRAHRYLVVA LSLMQKGEYI RCHHELNIAL KEFSAESTPE
     ESEKCARDHP PMPRGSGRST PLPPPSSSPI LPPPQLQFLC LYSLYMAGEC IKSTSSNPRK
     SSNPHLRTLR GRLLTLLEQQ RRSLSSSPAS IKSSMKPAPL SSASMAVGAP AYGDPFLCWL
     HGVVLRELGM KQESATYFLA ALCNHPMLWC AWEDLCTLVS RENQIEEIEA IIASLEPRFM
     SEIFLASVKA ALNVAPMSLV PPSLSTAAAA AMAQRSTSPH CGSLPRQPTS TLETQEQHYR
     PQHHQRRGES GVSPRLVNSW EALLERFPNN LFLLANLAGY YYNVKKDLEK AQSLYKRLHE
     MNPYRLESMD DYSIVLFLRG DRIGLSSLAQ QVYQIDPFRA ESNYVVGNYY VLMGAHDRGV
     LHFRRAVAAD PTFLAAWTLL GHAYLETKNS AAAVEAYRAA VDLDPRDYRG WYNLGQIYEL
     LQFYHHALYY YWHTTTLRPT DPRMWSAVAN CLDREGRTGE AVLCLERAEA HESSSSDYYP
     PLVHRLGLHY LGIRRLDRAV IYLEKLVLSE ARRREDVLFA IPHVVPYYLQ QARQLLDIPS
     RSPSYEPQPH HSTTAGGGDG QIPQTMESAM GATNASTGGN VYRSSLADQW LTADAATRQN
     IETRWEQATL CLTSSERHLE NFASVLGIPV ASAADNGARK STEYGDTGVS GSGGVAGVTM
     DERRSQHTLQ LACLYRELNK IRQYLTSQQE QVETAMKMRG GGNA
//