ID V5D508_TRYCR Unreviewed; 370 AA.
AC V5D508;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Tyrosine decarboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=TCDM_09801 {ECO:0000313|EMBL:ESS62526.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS62526.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS62526.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS62526.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|RuleBase:RU000382};
CC -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC {ECO:0000256|RuleBase:RU000382}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS62526.1}.
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DR EMBL; AYLP01000178; ESS62526.1; -; Genomic_DNA.
DR EnsemblProtists; ESS62526; ESS62526; TCDM_09801.
DR VEuPathDB; TriTrypDB:TCDM_09801; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR PANTHER; PTHR11999:SF70; AROMATIC-L-AMINO-ACID DECARBOXYLASE; 1.
DR PANTHER; PTHR11999; GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE; 1.
DR Pfam; PF00282; Pyridoxal_deC; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW Pyridoxal phosphate {ECO:0000256|RuleBase:RU000382};
KW Reference proteome {ECO:0000313|Proteomes:UP000017861}.
SQ SEQUENCE 370 AA; 40176 MW; AE6820892F69F205 CRC64;
MLKKAARCIG IRHIRVLKTV YSPHVHNYPM QPDMLKASLA EDVANGLYPL LVCGVFGART
TGAVDPLEEL AEICHRVKVW FHXXXXDASH SGLALAASAA YGFRDGAEQS GEFASVDEKD
AAAERMWEQC TSTFHRAALL ADSIHFGVST SFLPTLSANI SASLLYVADV AKVKVTMQGM
NAEDEAGGNT WCTPGMTDVA SLRLDAPEMR SNEIFRLALM LMPCIHASVG SAVRAHQATL
RYLERRLRAD GRFDCSLHAS CFGMVLFRWL TLADEETAGL MQRWSDLLAS SSAMNEAGGH
RYPHRVSLGL TQVQRRVYIC VALAAEGGDG DACVSRCDVD ALVDLLKTAA DEWRDISSSV
TSAISSKSKT
//
