ID V5E453_KALBG Unreviewed; 1729 AA.
AC V5E453;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Myosin class II heavy chain {ECO:0000313|EMBL:EST04971.1};
GN ORFNames=PSEUBRA_SCAF7g04483 {ECO:0000313|EMBL:EST04971.1};
OS Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Kalmanozyma.
OX NCBI_TaxID=1365824 {ECO:0000313|EMBL:EST04971.1, ECO:0000313|Proteomes:UP000019377};
RN [1] {ECO:0000313|Proteomes:UP000019377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GHG001 {ECO:0000313|Proteomes:UP000019377};
RX PubMed=24356824; DOI=10.1128/genomea.00920-13;
RA Oliveira J.V.D.C., dos Santos R.A.C., Borges T.A., Riano-Pachon D.M.,
RA Goldman G.H.;
RT "Draft genome sequence of Pseudozyma brasiliensis sp. nov. strain GHG001, a
RT high producer of endo-1,4-xylanase isolated from an insect pest of
RT sugarcane.";
RL Genome Announc. 1:E0092013-E0092013(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KI545893; EST04971.1; -; Genomic_DNA.
DR RefSeq; XP_016289960.1; XM_016439155.1.
DR STRING; 1365824.V5E453; -.
DR GeneID; 27421864; -.
DR eggNOG; KOG0161; Eukaryota.
DR HOGENOM; CLU_000192_7_16_1; -.
DR OMA; RCYFASK; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000019377; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000019377}.
FT DOMAIN 55..104
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 108..844
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 722..744
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1650..1729
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 915..1096
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1129..1170
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1199..1433
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1466..1497
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1536..1606
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1663..1702
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1715..1729
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 201..208
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1729 AA; 194993 MW; 2E1C192F3F72A8F3 CRC64;
MVDVVRTKSN LFRPSHRASP SVEANNAAQM AVAMPRPARG VGQSASDAAS AAEFASKKYV
WIPDANVGYV SAWVIKEEGE HSLCALQDGS NRTVPTFELS KMNPPKFDKA EDIADLTFLN
EASVVHNLRQ RYFSSLIYTY SGLFLVAVNP YHPLPIYTDA IVAAYKGRRR EENAPHVFAL
ADGAMRNMID NRENQSLLIT GESGAGKTEN TKKVIQYLAA IAADPAAHGS QSPANSLTPS
SSREVMDRIN GVEPVTSKRL GLLERQILQA NPILEAFGNA QTIRNNNSSR FGKFVRIEFT
SVGAIAGANI DWYLLEKSRV AIRSENERSF HIFYQLLRGG ESELKQKLLL TSLPDDYAYL
KGTRKDVEGV DDRAEWKLLR EALNTVGFSP EEQFNLFRVA AAILHIGNIQ LATDRSEQAR
ITNMPQIEKI CHVLGLPEQE FSNALLRPRV KAGREWVTSS RTMRQVSEEM AALSKFLYEK
AFGWLVERIN KALDRPTSKS SFIGVLDIAG FEIFEVNSFE QLCINYTNEK LQQFFNHHMF
VLEQEEYARE NIEWDFVNFG LDLQPTIDLI ESTSPIGILS CLDEECIMPK ASDTTFTEKL
YRTWGTNKDG SATDAAAAAA AAEKGLAHGS TKFGRTRFSQ GFVVKHYAGD VEYRTDGWLD
KNKDPLNDNL TRVMSESSDR FIASLFAEFA EVDEETSLAT APKRRVKRGA FRTVGQRHKE
QLNSLMGQLS STQPHFVRCI VPNSEKKPGK MDVPLVLEQL RCNGVLEGIR IARLGYPNRL
LFSEFRNRYE VLTPGIIPQG YMDGRKACQR MVEALELDKS LFKVGTSKIF FKAGVLAEME
ERRDSHLYDI FSRFGAACRM FTARRQMKKI LNRAAAVRTV QRNARLYVEL REWPWWQLYT
RVRPLLTATR HDEELKRKQL ELALVTERAE RDQKEREALE TLKFQLEAEK RKIEEELESE
RNLMLDKDQL LARSKERESA LEDDLAALQG DVDLLEGQLE KAIATQRATE QAHAELKSAF
DQAADHLLRL EAEQKAWKQR EDTFMRDLSQ HSTNAEQYRS ERQAFVADRD DLQRKLQEKE
QDLNRAHKRM LAAVQEVESK LMAEVQGREE EQKRAVQLED QTRQSSYQLS ELQRVAASHE
SRVKDKEQEV GQLQKQISSL SQERDVLSKQ LGDLNVKLNS LTFEAQSTRD EHAKTTEAKI
TLQRELDETR QLMEAKSSED VKTKEIHRMK EQELQTLREQ MSSVQKELLD SKHSSLEQIS
ALRAEISAAK KEVQAHGAAR QDAEAQVREA ESRVREADAK VAAAEKAKRE AEALLLEAQS
KSAVINRGLQ DALKTKDTLE KQLQASFTKH QDLEDALLEL ERRETNWKHK ADQISVELSA
ESKRRELLES AHKQAERNAN SLQQLVSGKD KEISGLKHEL TLAQQEMRKL QSMQNKTIVE
HVHVLEEAKK YTDRQLADAQ SKLGELAHYT KTLEKSKARL ASENEDLTRE LTRLQRAGDG
GMAASASVSN GLRSSVSTYG NIAPSTAKVG VDGKTTKKLE DKIAELTASL RQAAQQRDEA
LSNARRKDLQ ADELVSRTRR QYEQHVQELE RQLKNSQIAR SNTMTNLEEL VLAGHGSPVV
TGGASDGLRH QILDELRRGH EELEQDIAAK SDLLRSHKAP PAQAPTRGSS SYYVYDTKPA
RNGHPSNGSS GSSSSASELE KHTATLRGTA ARRNGDLINS PTRSVLTMR
//
