ID V5E7X6_KALBG Unreviewed; 681 AA.
AC V5E7X6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Sorting nexin MVP1 {ECO:0000256|ARBA:ARBA00014268};
DE Flags: Fragment;
GN ORFNames=PSEUBRA_SCAF3g03949 {ECO:0000313|EMBL:EST06426.1};
OS Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Kalmanozyma.
OX NCBI_TaxID=1365824 {ECO:0000313|EMBL:EST06426.1, ECO:0000313|Proteomes:UP000019377};
RN [1] {ECO:0000313|Proteomes:UP000019377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GHG001 {ECO:0000313|Proteomes:UP000019377};
RX PubMed=24356824; DOI=10.1128/genomea.00920-13;
RA Oliveira J.V.D.C., dos Santos R.A.C., Borges T.A., Riano-Pachon D.M.,
RA Goldman G.H.;
RT "Draft genome sequence of Pseudozyma brasiliensis sp. nov. strain GHG001, a
RT high producer of endo-1,4-xylanase isolated from an insect pest of
RT sugarcane.";
RL Genome Announc. 1:E0092013-E0092013(2013).
CC -!- FUNCTION: Required for vacuolar protein sorting.
CC {ECO:0000256|ARBA:ARBA00002474}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; KI545873; EST06426.1; -; Genomic_DNA.
DR RefSeq; XP_016291415.1; XM_016437886.1.
DR AlphaFoldDB; V5E7X6; -.
DR STRING; 1365824.V5E7X6; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_009058_1_1_1; -.
DR OMA; WEELIWF; -.
DR OrthoDB; 45524at2759; -.
DR Proteomes; UP000019377; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd07597; BAR_SNX8; 1.
DR CDD; cd06866; PX_SNX8_Mvp1p_like; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR028662; SNX8/Mvp1.
DR InterPro; IPR035704; SNX8/Mvp1_PX.
DR InterPro; IPR045734; Snx8_BAR_dom.
DR PANTHER; PTHR47554; SORTING NEXIN MVP1; 1.
DR PANTHER; PTHR47554:SF1; SORTING NEXIN MVP1; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF19566; Snx8_BAR_dom; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000019377};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 301..418
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EST06426.1"
FT NON_TER 681
FT /evidence="ECO:0000313|EMBL:EST06426.1"
SQ SEQUENCE 681 AA; 76689 MW; 85C3CE379D07E818 CRC64;
LEPACHVTTG PSLGAERNPA RPLRMRPRQH SSPAHMAPSV PDLYRHAWAA VSSSTSHDSF
ADPSEAEIPL GLLHKLLSSA GGLGPGSAEQ IVNAACKGSR CSRTDFFCAL GLLHQMQQGE
ALDAHIVQQR LAHGSLGAPT LNLSNLAIDT NSSHTFPPTA QAGFGRSEAR PPGPMREMSD
PWNASSTNHF NGTDSAPTYN RYDGLPQHHD ATDSAFRGGF ASNGTSGPSE RIRTNTGDTR
RSNQLYTHNE GSSADAFASP GREHTRSRQH TARHERPFSY MSETAEINAM DGAEDPAADL
PEDEVTVRLR SELEGFIIKH NVYIVTSSAR KSEVVRRYSD WLWLSECLVK RYPFRCLPVL
PPKRIAMPLA GRHLSADDLF IERRRRALER FLRMLTRHPM LREDKLVEVF FTETRPIAEW
KSSAPALFLD EEGLIKIVDE AERMSIPEDL ELKLTQQRQA IPELLERWTA MVALFERIVK
RNDAAAADYS RLNFSLLSVV ETTAKRWRPG SDNSKRTEET LSTTAAIFQD HSDMTSSRVS
AVSLSTLEGM KAQRDLLLSF RDLIGRIDRQ LVDPIDTLKK RIEAAQKKIT TLASTQNNNA
STQQEQATLS AQVKQDTQSI QKYLNRRIHA KKTIWEELIW FHWRFKAVEE DLQKFVRDET
FFLTTLTRLW EATEMKMKMI R
//
