ID V5EZP7_KALBG Unreviewed; 358 AA.
AC V5EZP7;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:EST09413.1};
GN ORFNames=PSEUBRA_SCAF11g01203 {ECO:0000313|EMBL:EST09413.1};
OS Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Kalmanozyma.
OX NCBI_TaxID=1365824 {ECO:0000313|EMBL:EST09413.1, ECO:0000313|Proteomes:UP000019377};
RN [1] {ECO:0000313|Proteomes:UP000019377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GHG001 {ECO:0000313|Proteomes:UP000019377};
RX PubMed=24356824; DOI=10.1128/genomea.00920-13;
RA Oliveira J.V.D.C., dos Santos R.A.C., Borges T.A., Riano-Pachon D.M.,
RA Goldman G.H.;
RT "Draft genome sequence of Pseudozyma brasiliensis sp. nov. strain GHG001, a
RT high producer of endo-1,4-xylanase isolated from an insect pest of
RT sugarcane.";
RL Genome Announc. 1:E0092013-E0092013(2013).
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI545853; EST09413.1; -; Genomic_DNA.
DR RefSeq; XP_016294402.1; XM_016434297.1.
DR AlphaFoldDB; V5EZP7; -.
DR STRING; 1365824.V5EZP7; -.
DR GeneID; 27416896; -.
DR eggNOG; ENOG502QT3Y; Eukaryota.
DR HOGENOM; CLU_031468_2_0_1; -.
DR OMA; WDYVVVT; -.
DR OrthoDB; 1548520at2759; -.
DR Proteomes; UP000019377; Unassembled WGS sequence.
DR GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:InterPro.
DR GO; GO:0015940; P:pantothenate biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR003710; ApbA.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR00745; apbA_panE; 1.
DR PANTHER; PTHR21708:SF42; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019377}.
FT DOMAIN 7..166
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 217..343
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 358 AA; 39428 MW; EC8A2594730B8A98 CRC64;
MSKPVHILIV GAGAVGCFYA SKLHQTHSER QILVSLVCRS NYAAIAANGV SLQTHSFGDY
HFTPHKVFSS IPEAGEAGID WDYVVVTTKA LPDVTNDAHD IRPVVKRGVE GSCIVLIQNG
VGIEEVHRVA YGENPIVSAV TVISAEQIKH GVIKQNRWTR ITMGTYTNGQ AKPNSLLSDS
ALLSKLTSTT DTHIKNLVAW FSATGIKDAE FSPELSLQQT RWHKLCINAS MNPSSVLSGG
TTNSRMALDP ELRTHLRACM DEIFLTAPKI LGIEFDEKKH ASPERILKST ERNTSGKPSM
LLDWQAGRPM ELEVILGNPL RIARRDGWEM PRLQTLYALL KMAQVRKRED AEGAKAKL
//
