ID V5FBY2_BYSSN Unreviewed; 625 AA.
AC V5FBY2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Glucose dehydrogenase, putative {ECO:0000313|EMBL:GAD94319.1};
GN ORFNames=PVAR5_2944 {ECO:0000313|EMBL:GAD94319.1};
OS Byssochlamys spectabilis (strain No. 5 / NBRC 109023) (Paecilomyces
OS variotii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX NCBI_TaxID=1356009 {ECO:0000313|EMBL:GAD94319.1, ECO:0000313|Proteomes:UP000018001};
RN [1] {ECO:0000313|Proteomes:UP000018001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=No. 5 / NBRC 109023 {ECO:0000313|Proteomes:UP000018001};
RX PubMed=24407650; DOI=10.1128/genomeA.01162-13;
RA Oka T., Ekino K., Fukuda K., Nomura Y.;
RT "Draft genome sequence of the formaldehyde-resistant fungus Byssochlamys
RT spectabilis No. 5 (anamorph Paecilomyces variotii No. 5) (NBRC109023).";
RL Genome Announc. 2:E0116213-E0116213(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD94319.1}.
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DR EMBL; BAUL01000086; GAD94319.1; -; Genomic_DNA.
DR AlphaFoldDB; V5FBY2; -.
DR eggNOG; KOG1238; Eukaryota.
DR HOGENOM; CLU_002865_7_2_1; -.
DR InParanoid; V5FBY2; -.
DR OrthoDB; 3382025at2759; -.
DR Proteomes; UP000018001; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000018001}.
FT DOMAIN 38..346
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 455..606
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT ACT_SITE 552
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-1"
FT ACT_SITE 595
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-1"
FT BINDING 262
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 625 AA; 68557 MW; C6727A1C74CA4C07 CRC64;
MNRRHRNPLS DPLHYATPQL HAGPPATYAT AQRTLRGYDY VIVGAGAAGC VLANQLSEDK
NISVLLLEAG GDHSKILASK IPLMFPKLFH GENDWKYFTV EQRALASRRL YWPRGRMIGG
STSMNAMMYH HCSKSDFDEW ASVHGCEGWS YDALAPYLRR MEKFTPNPGR PAIDSQHRGA
DGKWHTGYSW LSEISDKGFV AACEEVGIPA NPDVNTTRGS LGVTRFQTFI DSKGQRSSMA
TAFLSPEVLQ RPNLYVACHA QVTRVIFDTL STKEPTAIGV EFQTSRGGPR FEVHAKREVI
LCGGSVNTPQ TLLLSGIGPS EELADHRIPV VQENDAVGKN LKDHLCTTAM LCKAKSGKTL
DYLSSTVQAL PALIQWMLFG KGPLTNNIGE AAAFIRSTDY RFPQSLESPA EDNTSGPTAP
DLEVIGAPMA FIHHGEEAPI NGSNVFSMVP ISLRPRSSGT VTLQSRDAFD PPIIDPNYLS
DQDNNDLKVL LAGLRVCLKI MRSPAFQKFL EPVPVDDDPS SYWWPYSSSD IDAISEGDLI
RWMKEKAFTL YHPVGTARMG PTPDNSVVDM ECRVHGVNRL RVMDASIFPE QISGHPTAPI
GAMAFKLSDE IRKGVAAEVS ASAKL
//
